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BioTrust IC-5

The company behind BioTrust IC-5 claim that its users can lose over 30lbs without changing their diet. However, the ingredients are not backed by strong clinical evidence.

Below we have reviewed BioTrust IC-5 against our review criteria to help consumers make an informed decision.

BioTrust IC-5 Review

BioTrust IC-5 Pros
  • No serious side effects have been reported
  • Official website offers a money-back guarantee
  • Full ingredient quantities are revealed
BioTrust IC-5 Cons
  • The company do not offer a diet plan
  • Limited evidence of claimed testing on company website
  • None of the ingredients have been clinically proven to aid weight loss

BioTrust IC-5 is marked as ‘Rejected’ as it fails to meet all of the points on our ‘Approved Criteria’. To find out more about how BioTrust IC-5 performed against our criteria click here.

BioTrust IC-5 Review

BioTrust is a Texas-based company who claim to be committed to increasing the safety of the health supplements by introducing products that use natural ingredients and that have been tested by independent third parties. Biotrust describe their product as a synergistic blend of 5 unique ingredients that can dramatically enhance control of your blood sugar levels, stating to be ‘your body transformation’s best friend’.

Claimed weight loss benefits

BioTrust IC-5 is claimed primarily to help burn fat and support healthy blood sugar levels.

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How BioTrust IC-5 Works


The ingredients within IC-5 supposedly work together so that they can mimic the actions of insulin. In doing this they are thought to increase the rate of glucose metabolism in the liver and muscle cells, reducing the absorption of sugar in the intestine. As blood sugar levels are purportedly kept relatively low, the body may find another way of making energy and so pre-existing stores of fat are burned.

By increasing insulin sensitivity, supporting healthy blood sugar and partitioning carbohydrates to muscle not fat, BioTrust insists that IC-5 will help you shed weight quickly.

Cinnamon Extract

Derived from the bark of the cinnamon tree, this extract is thought to act as an insulin mimetic. It can help the body to more effectively manage your blood sugar levels following a meal rich in carbohydrates. It is also believed to stimulate the body’s insulin receptors meaning the sugar movement into muscle cells is enhanced; once in the muscle cells, the sugar can supposedly be burned as fuel and therefore supply energy. Cinnamon extract is said to keep blood sugar levels relatively low, which purportedly encourages the body to burn fat.

Pterocarpus Marsupium Extract

Pterocarpus marsupium is also known as the Indian Kino tree. It is the soluble fractions of its heartwood that supposedly provide the biological effects utilized in IC-5. An aqueous infusion of the heartwood is claimed to reduce glucose absorption from the gastrointestinal tract and improves insulin levels by stimulating insulin production from the beta cells of the pancreas. Like the other ingredients, pterocrapus marsupium extract supposedly works by controlling the body’s blood sugar levels and thereby stimulating fat loss.


Berberine is a rare plant alkaloid native to several plant species including Berberis Vulgaris. It has been used for many centuries in Ayurvedic medicine in India. Berberine purportedly works by regulating insulin secretion from beta cells, helping to increase the insulin response to sugar within the bloodstream, clearing sugar from the bloodstream faster. This is said to mean that the body then burns its stores of fat to create energy, helping you to lose weight.

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Key BioTrust IC-5 Ingredients


Cinnamon Extract

Derived from the bark of the cinnamon tree, cinnamon extract is believed to act as an insulin mimetic, enabling the body to effectively manage blood sugar levels following a carbohydrate rich meal. Sugar movement into muscle cells is supposedly enhanced as the extract stimulates the body’s insulin receptors. When it has reached the muscle cells it is thought to be burned as fuel and supply energy. This should, supposedly, keep the body’s blood sugar level low and encourage the body to burn stored fat.

Pterocarpus Marsupium Extract

Also known as the Indian Kino Tree, pterocarpus marsupium is thought to improve insulin levels by stimulating its production from the pancreas. Like the other active ingredients in IC-5, pterocarpus marsupium extract is believed to boost weight loss by controlling the body’s blood sugar levels and in turn, supposedly stimulating the loss of fat.


A rare plant alkaloid native to the Berberis Vulgaris, berberine has been used for centuries in Indian medicine. The substance is also thought to work by helping to increase the insulin response to sugar within the blood stream, clearing sugar from the blood stream quicker. The body then purportedly burns its stores of fat to create energy, which would aid with weight loss.

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Clinical Studies

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The BioTrust website states that they order independent third party clinical FDA approved testing on all of their products, yet the full details of this testing are not supplied on the website. Customers can supposedly contact the company who will provide this evidence. No studies can be found in scientific journals that have tested Biotrust IC-5 as a whole product, but there have been a few clinical studies into the ingredients used within IC-5.


In one study, subjects were fed rice pudding with or without cinnamon. The results showed that blood sugar increases were cut by over 50% with the addition of cinnamon, indicating that cinnamon can help to more effectively manage blood sugar.

Pterocarpus Marsupium Extract

One study has shown that pterocarpus marsupium is able to reduce post-prandial blood sugar, which is your blood sugar level 2 hours after eating a meal, by 21%. This may indicate that it could help to boost weight loss by stimulating fat burning in the body, though this is not a direct result of the study.


In a study published in the journal ‘Metabolism’, researchers used berberine head to head against Metformim. A three-month trial concluded that subjects taking berberine were found to have a 35% decrease in fasting plasma insulin and a 44.7% decrease in insulin resistance, indicating that it does indeed have the potential to alter blood glucose levels.

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BioTrust IC-5 Side Effects

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Before taking any supplement, it is useful to know of any potential side effects. The manufacturers of IC-5 state that there have been no reports of any serious side effects to the product. There have however been some reports of constipation, diarrhoea, and mild stomach aches while taking the product. There are some excluded groups who should not take this supplement, possibly due to its key ingredients – pregnant and breastfeeding women for example, as berberine is known to have serious side effects on babies and young infants.

The product’s website states that, so far, there are no known side effects of IC-5. It states that there have been independent third party clinical tests carried out on the safety of the product, but the full details of these tests are not available on the website. BioTrust say they take extreme caution when formulating their formulas to ensure there are no dangerous side effects. Nevertheless, it is possible to identify some side effects that may be associated with the ingredients in the product.

Cinnamon Extract

Although cinnamon extract is generally considered to be a safe ingredient, high doses can cause side effects; it be irritating to the skin and mucous membranes such as the stomach, intestine and urinary tract. This irritation can often lead to diarrhoea, vomiting, dizziness and drowsiness. Moreover, cinnamon may have an effect on blood glucose levels, and so diabetics should take care when consuming the ingredient.


Berberine is considered safe for short time use in adults, but can be extremely dangerous for babies and infants, potentially causing brain damage. Pregnant and breastfeeding women should also stay away from berberine for this reason. As with the other ingredients in this product, berberine can also have an effect on blood glucose levels.

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How to Use

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It is advised in the instruction guide that consumers take a capsule of IC-5 twice each day, around 15 minutes before eating a meal rich in carbohydrates. For example, one 15 minutes before lunch and another 15 minutes before dinner. However, it does not clearly state on the product website exactly how much time should be left in between each capsule.

The product’s website and its accompanying instruction guide give a clear list of the groups of people who should not use it. The product is not recommended for children under the age of 18, nor is it recommended for pregnant or breast-feeding women. You should consult a doctor before taking this product if you have diabetes. It is also advised that you visit your GP before beginning to take the product to check whether it is the right supplement for you, especially if you have any pre-existing medical conditions.

BioTrust equips its users with a clear instruction guide. The excluded groups are clearly stated and it is advised that you visit your doctor before taking the supplement if you have any medical conditions. The dosage is also easy to follow and appears simple enough; however, there could be more details as to how long to leave in between each capsule. The user is told not to exceed the recommended dose.

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Who Makes It

IC-5 is manufactured by an American company called BioTrust, based in Austin, Texas. The official website states that two supplement enthusiasts founded the company in 2011, supposedly after learning that the health supplement industry is in US is not as well regulated as it should be. BioTrust describes itself as providing honest nutrition which is properly tested and regulated.

The company website states that they are committed to three things. Firstly, to only using top quality, all natural ingredients free from hormones, antibiotics and artificial colours and preservatives. Secondly, they commit to creating products that work because they contain the precise dose of each key ingredient and finally to using strict quality control measures that ensure each and every BioTrust product meets label claims and is guaranteed to be potent and pure.

To make sure that their products are safe to use and work well, BioTrust claim to order testing on their supplements to be carried out by independent third party laboratories.

There are few complaints regarding the efficiency and professionalism of the company, although it is possible that the reviews on the official website are biased. BioTrust appears to be an established company, invested in improving the diet supplement market and making it safer for supplement users. They also offer a money-back guarantee on products.

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Where to Buy BioTrust IC-5


Unfortunately, this product is not available to buy from UK high street stores and currently is only available to purchase online. We recommend that you buy this product directly from its manufacturers BioTrust as they have the best deals and prices for this product, have positive feedback in terms of shipping and delivery, and send out a free recipe guide with all orders.

By purchasing from the official website, there should not have been any third party tampering with the product or selling you something that is not the real thing, as can be the case with products sold on marketplaces. By buying the product directly from its manufacturer, you will also receive a free copy of ‘53 Fat Burning Smoothies and Milkshakes’. BioTrust have some deals on their product with one bottle costing $69 (£42.87) but 6 bottles for the price of $49 (£30.44) per bottle.

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Does BioTrust IC-5 Meet our Approved Criteria

Money-back-guarantee: Yes, there is a one-year money-back guarantee on the official website.

One-off payment: Yes, $69 (£45.30) for one bottle.

Manufacturing Standard: The official website states that the manufacturing is GMP certified.

Accompanying Diet Plan: No, but customers get a free copy of a book containing ‘fat burning smoothies’ recipes.

Ingredients and quantities disclosed:Yes, the full label is available.

Company contact details readily available: Yes, including a phone number, email address, and postal address.

BioTrust IC-5 does not meet our ‘Approved’ criteria as it does not come with an accompanying diet plan.


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Overall Verdict

Whilst clinical studies do indicate that the ingredients in Biotrust IC-5 have the potential to alter blood glucose levels, there is no direct evidence that they can boost weight loss. Only a small number of studies are available for the main ingredients in the product, so long-term side effects may not be fully understood. It is claimed that the company aims to provide safe products for its customers and it does offer a money-back guarantee. The official website does however lack some information, particularly regarding the studies that they pertain to.

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7 responses to “BioTrust IC-5”

  1. Shane Allard says:

    I am interested in IC-5 for lowering my blood sugar levels naturaly. I am a Type II diebetic and do not want to have to take insulin shots down the road. I am 6 ft tall at 190 lbs and work out 3 times a week so I am not interested in losing weight just lowering my blood sugar levels.. Please suggest a natural way of achieving this while still taking medformin prescibed by my doctor.


    • Barbara / BioTrust Nutrition says:

      Hello Shane,

      Thank you for your interest in IC-5! My name is Barbara from BioTrust Nutrition. I am sorry that you did not get a response to your question. This website is not is not affiliated with BioTrust Nutrition.

      Your goals to improve your health naturally are inspiring. I hope that you have seen success throughout this last year.

      While the active ingredients in IC-5 has been clinically shown to increase insulin sensitivity and lower blood sugar in response to a carbohydrate meal, IC-5 does not treat, cure, or prevent any disease, such as diabetes. If you are on medication, you should continue to take your medication under the direction of your physician and must consult with your physician before using IC-5. That said, don’t worry as you’re always protected by our 1-Year Money Back Guarantee and can return the product for a full refund if needed. If you have any medical condition, such as diabetes, you should not stop your medication,adjust your diet, or your carbohydrate intake without consulting with your physician.


      Barbara T.
      Quality Assurance Analyst
      BioTrust Nutrition

  2. George Fernandes says:

    I wish to buy IC-5 but there is delivery charges. I live in UK.

    • Barbara / BioTrust Nutrition says:

      Hello George,

      Thank you for your interest in IC-5! My name is Barbara from BioTrust Nutrition. I am sorry that you did not get a response to your question. This website is not is not affiliated with BioTrust Nutrition.

      If you are still interested in this product, please know that shipping is not typically waived. However, you receive a discount by enrolling into the Ship-N-Save program (available for 1 or 3 bottle bundle orders). In addition to the discounted rate, this automatic monthly shipment benefits international customers because the shipping is waived. Ship-N-Save can be postponed or cancelled at any time.

      Barbara T.
      Quality Assurance Analyst
      BioTrust Nutrition

  3. Barbara / BioTrust Nutrition says:

    Thank you for your interest in BioTrust Nutrition. Please visit the official BioTrust website to view all of our products and forum.

    If you have any questions or concerns, please contact customer support directly. Our team is happy to assist you M – F 8AM – 9PM EST, Sat & Sun 10AM – 9PM.

    Call us toll free at 1-800-766-5086 or send an email to

    Thank you for being valued customers!

  4. Ken says:

    I am a type II diabetic. I have been on Metformin for several years. A friend gave me IC-5 and I was shocked at how much it helped control my blood sugar. I test about 5 times a day and I can no longer deny that IC-5 is far more affective than Metformin. Though there has not been a lot of testing on this product, I like the idea that it is all natural.

  5. rachel toseland says:

    I have been taking IC5 Bellytrim XP and Leptin for 3 weeks now as directed by Biotrust nutrition. So far although I eat a reasonably healthy diet (no processed food) I am failing to get the promised results. Rather than losing weight I have gained around 7 pounds!

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