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BioTrust LeptiBurn

BioTrust claim that this supplement will keep your body optimised for maximum fat loss throughout the weight loss process. Unfortunately the ingredients in the product are largely understudied.

Below we have reviewed Biotrust Leptiburn against our review criteria to help consumers make an informed decision.

Biotrust Leptiburn Review

BioTrust LeptiBurn Pros
  • Some of the ingredients have been scientifically tested
  • One-year money-back guarantee offered
BioTrust LeptiBurn Cons
  • Not stocked by any reputable UK-based retailers
  • Most of the ingredients have only been subject to very early-stage research

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Biotrust Leptiburn Review

The manufacturers of the BioTrust LeptiBurn weight loss supplements claim that the product offers advanced fat-burning hormone support and works to powerfully help you lose weight by increasing the production and sensitivity of the leptin hormone found in the body. The manufacturer’s also claim that BioTrust LeptiBurn works to achieve weight loss naturally by supporting accelerated fat loss and diminishing weight loss plateaus. The product’s appetite suppressing formula is claimed to combine six different natural ingredients which include Irvingia Gabonensis, Oleanolic Acid, Modifilan, Panax, Notoginseng, and YerbaX (yerba mate and green tea extracts) which the manufacturer’s believe to be designed to help an individual lose weight in a quick, safe and effective manner.

Claimed weight loss benefits

The manufacturers of the BioTrust LeptiBurn supplement claim that the product has four of the main weight loss factors: Fat Burning, suppressing the appetite, working as a metabolism booster and being safe and effective to use as part of a diet plan. The manufacturer clearly states that the product is not a miracle pill, and that it should be used in combination with regular exercise.

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How Biotrust Leptiburn Works

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The manufacturers of the BioTrust LeptiBurn supplement claim that the product contains six scientifically-backed herbal ingredients designed to support leptin production and sensitivity in the body. These ingredients are; Irvingia gabonensis, Oleaeuropaea (Olive leaf extract), laminaria japonica (Brown Seaweed extract), Green tea extract and Yerba mate extract.

The manufacturers of the BioTrust LeptiBurn supplements claim that the combination of these six herbal ingredients result in priming the body for accelerated fat loss “every hour of every day” as they boldly state on their website. It is also claimed that as the ingredients in the BioTrust LeptiBurn supplement are all natural and herbal, they are not only free of any allergens, but posses little to no negative side effects, apart possibly from the stimulant effect of the green tea extract.

Increasing both the production and sensitivity of the leptin hormone in the body is an important issue which the BioTrust LeptiBurn supplement is concerned with. The manufacturers of the product claim that when following a weight loss diet, the levels of the body’s most important fat burning hormone – leptin – rapidly declines, and the result of this is slower fat loss and possible weight loss plateaus. Those who are classed as overweight are thought to have become leptin resistant according to the manufacturers. The manufacturers also claim that in order to burn fat, your body is dependent on two things; firstly, high levels of leptin, and secondly, having highly-sensitive leptin “receptors.” Leptin functions in the body protecting the body against starvation, and when opting for a decreased food intake then usual when dieting, the body works by viewing any stored fat in the body as very important for survival.

It is understandable why one may be sceptical about the BioTrust LeptiBurn supplements, as it is very important for your body to store some fat which is needed to provide warmth and energy. BioTrust LeptiBurn supposedly works to prevent leptin resistance by working to make the leptin receptors in the body more sensitive and responsive to the presence of leptin in the body. The manufacturers claim that the BioTrust LeptiBurn supplement indicates to the body that it must produce leptin, regardless of whether you are within normal or below normal calorie intake, and that weight loss changes can be seen within the first month of using the supplement. It is advised that you do not eat far below the recommended calorie intake when dieting because this may possibly lead to some side effects such as fatigue.

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Key Biotrust Leptiburn Ingredients


Green Tea Extract

The BioTrust LeptiBurn supplements claim to contain 350mg per serving of Green tea extract. Unlike some other weight loss claiming natural ingredients, Green Tea extract is an ingredient which is commonly used to aid in weight loss. Green Tea Extract can be made from the leaves of the Camellia sinensis plant. It is believed that Green Tea has a wide range of benefits other than possibly aiding weight loss. These include, lowering blood pressure, decreasing cholesterol, increasing mental alertness and reducing the risk or delaying Parkinson’s disease.

Green Tea also contains 2-4% caffeine which may affect the body’s alertness. Caffeine is believed to be able to stimulate the nervous system, heart and muscles by increasing the release of certain chemicals in the brain called “neurotransmitters”. This can be linked to boosting the metabolism and increasing energy levels. However although many manufacturers of weight loss products claim that Green Tea can be used for weight loss, there is insufficient evidence available to support this claim.

Irvingia Gabonensi

Irvingia gabonensis is another main ingredient in the BioTrust LeptiBurn weight loss claiming supplement, and is believed to support leptin sensitivity according to the manufacturers of the supplement. It is said to do this by inhibiting the production of C-reactive protein (CRP), a chemical in the body that has been linked with the development of leptin resistance, by up to 52%. It is believed that the seeds of the Irvingia gabonensis may help in lowering cholesterol as they contain a high fibre content which increases the removal of cholesterol from the body.

Irvingia gabonensis is a tree native to West Africa, and the fruit which grows on it is similar to a mango and used for food. The seeds are often used in traditional medicines. It is believed that Irvingia gabonensis can be used for weight loss, to lower cholesterol levels as well as improving control of diabetes. According to WebMD. Each serving of the BioTrust LeptiBurn supplements is claimed to contain 150mg of Irvingia gabonensis


Oleaeuropaea, also know as Olive leaf extract, is also present in the BioTrust LeptiBurn supplement. In general and throughout time olive leaves have been used predominantly in the Middle East as a herbal treatment for various health problems, and has been linked to better health and lower risk of chronic diseases. Oleanolic acid is a compound extracted from olive tree leaves and the manufacturers of the BioTrust LeptiBurn supplement believe it to have a stimulatory effect on a specific gut peptide called Glucagon-like Peptide-1 (GLP-1). Oral doses of this specific peptide are believed by some as being closely linked to increasing leptin production in the body. Each serving of the BioTrust LeptiBurn supplements is claimed to contain 150mg of Olive leaf extract.

Brown Seaweed Extract

Brown seaweeds mostly grow in the cold waters of the Northern Hemisphere and form a large and diverse group of marine algae. Some forms of brown seaweed can be eaten and are believed to be nutritious, such as kelp. It is believed that there are numerous health benefits associated with brown seaweed when taken in supplement form. The manufacturers of BioTrust LeptiBurn claim that brown seaweed extract has been shown to stimulate the increase of leptin production in fat cells by up to 18%. This is through brown seaweed extract’s supposed ability to stimulate the Thyroid Stimulating Hormone (TGH) in the adrenals. It is thought by some that the stimulation of the Thyroid Stimulating Hormone in turn stimulates the production of leptin in the fat cells. Each serving of the BioTrust LeptiBurn supplement is claimed to contain 200mg of brown seaweed extract.

Yerba Mate

Each serving of the BioTrust LeptiBurn supplements is claimed to contain 83mg of Yerba mate standardised extract. Yerba Mate originates from South America and is a very popular form of tea known for its potential health benefits. It is a species of the holly family (Aquifoliaceae).

It is commonly drunk as a tea made by steeping the ground leaves and stem of the yerba mate plant. Yerba mate is a central nervous system stimulant containing caffeine, but it also contains a number of other nutrients, including antioxidants, amino acids, polyphenols, vitamins and minerals. Yerba mate is touted as being a safe and effective nervous system stimulant with few side effects and many health benefits. It is believed to enhance the fat burning effects of the supplement according to the manufacturers of BioTrust Leptiburn, as well as to increase the resting metabolic rate. The manufacturers of BioTrust LeptiBurn also claim that yerba mate combined with the green tea extract helps in increasing energy and alertness.

For more information on Yerba Mate, we recommend you read our Can Yerba Mate Help You To Lose Weight? article.

Panax notoginseng

The last of BioTrust LeptiBurn’s ingredients is claimed to be panax notoginseng, also known as panax pseudoginseng, Chai-Jen-Shen and Shan Qi. It is a commonly used traditional Chinese herb which has recently been said to have unique metabolic properties, including naturally increasing leptin sensitivity according to the manufacturers of BioTrust LeptiBurn. The Panax pseudoginseng is a plant, the root of which is commonly used in traditional medicines. More commonly it is used to stop or slow down bleeding such as nose bleeds and to relieve pain, reduce cholesterol and blood pressure. There is not much of an association with weight loss to be exact. It is stated by WebMD that those with hormone sensitive conditions such as breast cancer or uterine fibroids shouldn’t use panax notoginseng.

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Clinical Studies

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The manufacturers of the BioTrust LeptiBurn weight loss supplements claim that the supplement formula has been scientifically designed to approach leptin from two problematic angles: production and sensitivity. Trials must follow a set of rules, known as protocol in order to ensure they are well designed and as safe as possible. It is important that a study measures the correct things in the correct way, and that the results are meaningful. In many cases it has been found that clinical trials can be biased, and not necessarily reflect the actual results.

As we have mentioned previously, the supplement blends together Green Tea extract, yerba mate extract, panax notoginseng, brown seaweed extract and Irvingia gabonensis. While clinical studies have suggested that some of the individual ingredients in the supplement may help with improving leptin sensitivity, these studies have not been done on the complete BioTrust LeptiBurn product itself. Some of the studies have also only been completed on mice rather than humans and so research on these ingredients is still in the very early stages.

The manufacturers of BioTrust LeptiBurn do offer examples of studies carried out on some of the ingredients in the BioTrust LeptiBurn supplement.

As there have been no clinical studies carried out on the BioTrust LeptiBurn supplement as to date, we can take a look at a clinical trials carried out on some of the ingredients such as Irvingia Gabonensis and panax notoginseng.

Irvingia gabonensis

A clinical study was carried out on the effects of Irvingia gabonensis seeds on body weight and blood lipids of obese individuals in Cameroon in 2005. The aim of this study was to examine and evaluate the efficacy of Irvingia gabonensis seeds in managing obesity. The study was carried out on 40 overweight participants around the mean age of 42.4 years. It is important to note that although this is a study which involves humans, it was still a rather small study. Twenty-eight of the participants were given Irvingia gabonensis (IG) in 1.05g doses three times a day for a month, while twelve participants were given placebos which followed the same schedule.

The results found that there were effects on body composition, blood pressure and blood lip components. At the end, the mean body weight of the IG group was decreased by 5.26 ± 2.37% and that of the placebo group by 1.32 ± 0.41% . Irvingia gabonensis was found to induce a decrease in weight of 2.91 ± 1.48%. The difference observed between the IG and the placebo groups was significant. The obese patients under Irvingia gabonensis treatment also had a significant decrease of total cholesterol, LDL-cholesterol, triglycerides, and an increase of HDL-cholesterol. On the other hand, the placebo group did not manifest any changes in blood lipid components. To conclude the study found that the Irvingia gabonensis seed may help weight loss.

Olive leaf extract (Oleanolic acid)

Research has shown that an oral dose of this compound extracted from olive leaves may have a stimulatory effect on a specific gut peptide called Glucagon-like Peptide-1 (GLP-1). In one 24-week randomised, double-blind study carried out on overweight individuals it was found that co-administration of recombinant human leptin and the amylin analog pramlintide elicited 12.7% mean weight loss, significantly more than was observed with either treatment alone. What this clinical study was able to provide was evidence that amylin agonism restored leptin responsiveness in diet-induced obesity.

Brown Seaweed extract (Modifilan)

According to the manufacturers of BioTrust LeptiBurn, it is stated that the ingredient Modifilan has shown to stimulate increased leptin production in fat cells by up to 18% through its ability to stimulate Thyroid Stimulating Hormone (TSH) in the adrenals. A study to help support this claim was carried out in 2003 looking at the effects of kelp supplementation on thyroid function in euthyroid subjects. The double-blind prospective clinical trial involved 36 healthy euthyroid subjects who were randomly assigned to receive placebo (4 alfalfa capsules per day), low-dose kelp (2 kelp capsules and 2 alfalfa capsules per day), or high-dose kelp (4 kelp capsules per day) for 4 weeks.

The study found that the short-term dietary supplementation with kelp significantly increased both basal and post-stimulation TSH. However further studies are needed to determine whether the ingredient will have a long term effect or whether long term kelp supplementation may result in clinically significant thyroid disease.

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Biotrust Leptiburn Side Effects

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The manufacturers claim that because BioTrust LeptiBurn only uses natural ingredients there are almost no side effects at all, except possibly for those with sensitivity to caffeine. It is important to remember that natural ingredients can cause side effects, sometimes very severe, and every individual is different. An increased intake of caffeine can for some result in concerns of increased blood pressure. Some reviewers of the product have claimed that they took one capsule a day instead of two because of the strong caffeine intake of the supplement. It is also possible that increased caffeine intake may cause feelings of jitteriness and rapid heartbeat.

The manufacturers of BioTrust LeptiBurn claim that the product as with every BioTrust product is all-natural and completely free of gluten, dairy, wheat, soy, egg, fish, crustacean shellfish, tree nuts, and peanuts. It also contains NO sugar and NO artificial sweeteners, flavours, colours or preservatives. They also claim the supplement is 100% vegetarian-friendly because the company use only Veggie-capsules. It is advised that as a precaution those with concerns should consult their physicians before taking the supplement.

If you take prescription medicines or have a medical condition you are also advised to consult your doctor. It is also important to note that due to any of the ingredients not having received much research on safety, as a general precaution those with liver or kidney disease, those who are pregnant, nursing or under the age of 18 are also not advised to take the supplement. BioTrust mention on their website that the statements on their website have not been evaluated by the Food and Drug Administration (FDA).

Increased Blood Pressure

Those who already have a high caffeine intake already should be aware that the caffeine in green tea might increase blood pressure in people with high blood pressure. However, it is sometimes thought that this is not a concern in people who regularly drink green tea or other products that contain caffeine.


The caffeine which is present in both green tea and yerba mate extract is a strong stimulant, and it can stimulate your central nervous system. This effect can cause the jitteriness and nervousness that people have experienced.

Birth defects

It has been suggested that one of the chemicals in panax ginseng has caused birth defects in research animals, therefore those who are pregnant or breast-feeding should not take the BioTrust LeptiBurn supplement.

Headaches and Dizziness

The caffeine in the product has also been linked with headaches and dizziness in some people. Headaches may also be experienced when you stop taking the product as the body can become dependent on caffeine and so the consumer may suffer from withdrawal symptoms.

Upset Stomach

As with many weight loss supplements and new chemicals entering the body, a very possible side effect is having an upset stomach. Several of the ingredient in the product have been associated with nausea and digestive problems; be wary of taking this product if you have any pre-existing digestive conditions.

There have only been a small number of studies carried out on the ingredients combined in BioTrust LeptiBurn, therefore the precise side effects that may be experienced are not fully understood. Be sure to contact a doctor if you are concerned about taking the supplement, particularly if you are taking any medication or have a pre-existing health condition of any kind (particularly if you suffer from diabetes, kidney problems, liver problems, or have a history of cardiovascular problems). Some of the ingredients are much understudied and so their safety is not yet known.

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How to Use

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The manufacturers of BioTrust LeptiBurn give a good amount of information about the supplement, how it should be used and for how long. BioTrust recommend that the supplements should be taken as long as the individual is following a reduced calorie weight loss diet, which implies that the supplement will not work effectively to aid weight loss if the individual is not on a reduced calorie diet.

It is also stated however, that once an individual has reached their weight loss goal they are no longer required to follow a reduced calorie diet and the use of the BioTrust LeptiBurn supplement is no longer necessary. It is also claimed by the manufacturers that you should be able to see a visible difference within 30 days of using the supplement, and even more profound results after prolonged and continued use.

Each bottle of BioTrust LeptiBurn should contain 120 Veggie capsules, and the directions state that you should take two capsules with breakfast and two capsules with lunch. You should not take the supplement within 6 hours of bedtime and never exceed the recommended serving size or suggested use. Those who are looking to lose more than 10 pounds are suggested to first buy 3 bottles of the supplement according to the manufacturers. Those looking to lose more are recommended to buy 6 bottles of the supplement.

The information given by the manufacturers is helpful in gaining a solid idea on exactly how the product should be used and by whom. As many weight loss claiming supplements would suggest, the BioTrust leptiBurn supplement is best used in conjunction with a calorie-reduced diet and a regular exercise program. Always remember to drink 8 oz or more water with each dosage.

The appropriate dose of the active ingredients in the BioTrust LeptiBurn supplements may depend on several factors such as the user’s age, health, and several other conditions. It is also important to keep in mind that natural products are not always necessarily safe and dosages can be very important. Be sure to follow relevant directions on product labels and consult your pharmacist or physician or other healthcare professional before using.

It should be remembered that BioTrust LeptiBurn isn’t a miracle pill as the manufacturers also acknowledge. As with all weight loss claiming supplements you should add some lifestyle changes in order to feel the full benefit. Firstly, you should adopt a healthier lifestyle by taking up regular exercise. Getting active doesn’t mean having to go to the gym, you can find a range of activities to do at home which cater for busy mums to older adults and even kids. To find an activity that might suit you check out this NHS webpage. Finally, you should always make sure that you drink plenty of water throughout the day. Not only does it help to avoid constipation, sometimes your body confuses thirst for hunger so by keeping hydrated you reduce the risk of overeating. It has been advised that you should drink one large glass with each meal and one small glass between meals.

There are certain types of people who shouldn’t take the BioTrust LeptiBurn tablets, these are:

-Those who are pregnant or likely to get pregnant
– Breastfeeding mothers
-Those with high blood pressure or heart conditions
-Those who have a BMI less than 18.5
-Women who are breastfeeding
-Those under the age of 18
-Those over the age of 60

You should also consult your doctor before taking the tablets if you:
-Have diabetes
-Use cholesterol reducing medication
-Have an existing medical condition
-Are taking any anti-depressants

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Who Makes It?

BioTrust is the name of the company behind the BioTrust LeptiBurn supplements. The company provide information about itself on the ‘our story’ page of their website where it is claimed that the co-founder of the BioTrust Nutrition is Josh Bezoni and his partner Joel Marion who decided to set up the company after using many supplements themselves and being surrounded by scams and unfair prices.

Their website provides details of exactly why they decided to start the BioTrust Nutrition company. The company also offers other supplements relating to sexual health, beauty and personal care, vitamins and supplements, sports and fitness as well as diet and weight loss.

It is stated that the company has a commitment to using only top-quality ingredients that are free from hormones, antibiotics, artificial sweeteners, colors, flavors and preservatives, making products that work because they contain effective levels of each key ingredient for real results, and strict quality control measures that ensure each and every BioTrust product meets label claims and is guaranteed potent and pure.

The company also state that unlike many other companies they have very good quality control, and hire qualified registered dieticians, PhDs and Medical Doctors to formulate their products based on the latest research, and have a 7-stage research and testing protocol before a product can become “BioTrust Approved and Certified.”

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Where to Buy Biotrust Leptiburn


There are not many places where you can purchase the BioTrust LeptiBurn supplements. The supplement appears to be only available to buy online on what appears to be the manufacturer’s website. The BioTrust LeptiBurn supplement is also available to buy through Amazon, however it is still sold through the product’s manufacturers BioTrust. The manufacturers do suggest that you buy the product straight through them as they offer a 1 year money back guarantee if you are not 100% satisfied with your product.

The BioTrust LeptiBurn supplement is not stocked by trustworthy health retailers such as Boots or any UK based retailers..

The BioTrust website appears to be one of the only sites where one can purchase the BioTrust LeptiBurn weight loss supplements. BioTrust appears to be an established US based health supplement company, mentioned in Men’s Fitness magazine. One bottle of the BioTrust LeptiBurn supplement is on sale for $69 on the manufacturer’s website. A discounted 3 bottle option of the product at $59 per bottle is advised for those looking to lose more than 10 pounds, as well as a discounted 6 bottle option of $49 per bottle for those looking to lose more.

The BioTrust LeptiBurn supplement is also sold online on Amazon, again by the manufacturers BioTrust, but for the non-discounted price of $74.99 per bottle with free shipping. It has received quite mixed reviews by customers on Amazon.

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Does Biotrust Leptiburn Meet our Approved Criteria

Money-back-guarantee: The official website states that a one-year money-back guarantee is available.

One-off payment: Yes, though it can only be purchased from the official website.

Manufacturing Standard: Made in an FDA-approved laboratory.

Accompanying Diet Plan: There is no mention of an accompanying diet plan, but each order comes with a free book of smoothie recipes.

Ingredients and quantities disclosed: Yes, a full ingredients list is available.

Company contact details readily available: Contact information is available on the official website.

Biotrust Leptiburn does not meet our ‘Approved’ criteria as there is diet plan.

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Overall Verdict

The BioTrust LeptiBurn supplement is claimed to target several areas of weight loss and the official website goes into detail regarding how it is thought to work. That said, the product hasn’t been tested as a whole and many of the ingredients remain understudied. The official website also claims that it should not cause side effects, but this is not likely to be the case – particularly due to the caffeine content of the capsules. The company is fairly established, but the official website is the only place (apart from Amazon) that the supplement can be purchased.

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