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Addium is advertised as a ‘brain enhancer’ that can increase energy levels and boost alertness. It is claimed to be superior to energy drinks. Evidence to support any potential weight-loss effects of the product is however very limited.


Addium Pros
  • There are some clinical trials that have associated caffeine (an ingredient in Addium) with weight loss
  • Most of the ingredients have been linked to maintaining good mental health
  • Sold via Amazon, offering a level of security (e.g. with postage and refunds)
  • Ingredients have not been associated with severe side effects in people of good general health
Addium Cons
  • No clinical studies have been undertaken on the product as a whole
  • The majority of the ingredients in the product have not been shown to aid weight loss
  • The product does not have an official website, so lots of important information is unavailable
  • No money-back guarantee available

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Addium Review

Addium is advertised principally as a ‘brain enhancer’. It belongs to a group of supplements known as ‘nootropics’, which includes a selection of different supplements designed to improve cognitive function, such as memory and focus. These substances are understood to alter the transmission of neurotransmitters in the brain. Well-known stimulants, such as caffeine, also belong to this group.

Few commercially available nootropics have been sufficiently clinically tested, and Addium is no exception. Side effects might occur but potential adverse effects are not well documented, particularly in the long term. The product has not been subject to any clinical testing and whilst an ingredients list is provided, the amount of each ingredient in the proprietary blend is not disclosed.

Addium Claimed weight loss benefits

The main claims of the product relate to its potential cognitive enhancement properties. Whilst there does not appear to be an official website for the product, the Amazon page claims that Addium can increase energy levels. It is not specifically advertised as a weight loss product, but due to this claimed quality, Addium could be described as a metabolism booster. Vitamin B6 and acetyl L-carnitine, two of the ingredients in the product, are thought to act as fat burners. Caffeine, also present in Addium, has been claimed to act as an appetite suppressant, as well as to boost energy and the metabolism, and increase fat burning.

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How Addium Works


The product as a whole is advertised as a brain enhancer, not as a weight loss supplement. That being said, there are claims on sites selling the product that it works to increase energy levels, which, in turn, could support weight loss. Moreover, a number of the ingredients in the product are often included in weight loss supplements because of their claimed benefits with regards to several of the key areas of weight loss. These include: metabolism boosting, fat burning, and appetite suppression. The specific quantities of each ingredient (apart from vitamin B6) are, however, not disclosed on the ingredients list, so whether or not they will have an effect cannot be stated with any certainty.

How Each Ingredient Works

Vitamin B6

Vitamin B6 has been claimed to act as a fat burning ingredient. It has also been said to increase energy levels and boost the metabolism in turn. All B vitamins are water-soluble; this means that the body does not absorb them and instead, they leave via the urinary tract. Vitamin B6 has been claimed to help with the fat burning process by providing bodily cells with fuel. It has also been claimed to increase the amount of food digested fully rather than being stored in the body as fat when combined with other ingredients, such as zinc. Evidence in support of these claims is lacking, particularly with regards to the specific processes involved. Supplementation with vitamin B6 has however been shown in one small-scale clinical trial to improve the maintenance of fat-free mass during periods of weight loss.


L-carnitine is used by the body principally to help with the breakdown of fat cells (adipocytes). Fat cells accumulate when a person consumes more calories than they expend and L-carnitine is said to be important to the process of lipolysis – the breakdown of fat for use as energy. Supplementing the diet with L-carnitine has therefore been said to increase the efficiency of the fat-burning process. Despite these claims and the common addition of L-carnitine to weight loss supplements, the ingredient has not been proven to aid weight loss in reliable clinical studies. A few scientific studies have been undrtaken to test whether or not L-carnitine has an impact on weight loss, but with negative results.


Like L-carnitine, L-theanine is an amino acid that is sometimes claimed to boost weight loss. When combined with catechins, such as those found in green tea, theanine has been said to increase thermogenesis (the internal body temperature) and in turn, have a fat-burning effect. In Addium however, green tea antioxidants are not present. The other claim behind L-theanine is that it can indirectly aid weight loss by increasing a person’s mood and reducing effects of anxiety and depression. It has been said that the ingredient can help to reduce emotional eating resulting from stress and anxiety. There is no strong evidence to this effect to date.


Caffeine is a stimulant and is amongst the most common ingredients found in weight loss supplements. Manufacturers have touted caffeine as a weight loss substance for a number of reasons. It is claimed to increase energy levels and as such, increase the metabolic rate, meaning that the body might expend more energy than usual. It has also been said to have fat burning abilities and to suppress the appetite by altering the concentrations of neurotransmitters in the brain. Solid evidence in support of many of these claims is lacking, though the ingredient is known to give a short-term energy boost and some studies have suggested that this can result in a slightly increased metabolic rate and fat burning.

Rhodiola Rosea Extract

Rhodiola rosea extract has been claimed to aid weight loss in two ways. As with L-theanine, it has been said that the ingredient can contribute indirectly to weight loss by improving mental state of mind and reducing anxiety and depression-induced comfort eating. In terms of direct weight loss, some state that rhodiola and its chemical components, rosavins, can act as a fat burner. It is said to increase the efficiency of enzymes that are involved in the breakdown of fat cells, helping fat to be used as energy more efficiently. Some clinical studies on the ingredient will be discussed in the ‘clinical studies’ section below, but not conclusively prove that rhodiola can aid weight loss.

Bacopa Monnieri Extract

Though sometimes described as having weight loss effects, precisely how Bacopa monnieri is thought to achieve this is rarely disclosed. It’s main effects are believed to be on the brain, again helping to improve mood and reduce anxiety; it can be assumed therefore, that it is thought to aid weight loss by reducing stress-induced eating.

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Key Addium Ingredients

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An ingredients list can be found on the bottle of Addium, which can be seen in pictures on retailer websites such as Amazon. The label shows the quantity of vitamin B6 and of the proprietary blend, which contains five more ingredients. The precise quantity of each of the ingredients in the proprietary blend is however not disclosed. Most ingredients have some association with weight loss, though this association is weak and has not typically been proven in clinical studies.

Active Ingredients

Vitamin B6

Belonging to the B-vitamins, vitamin B6 is required for human health. Vitamin B6, also known as pyridoxine, must be consumed in the diet because it is water-soluble, meaning that it will not be absorbed by the body, instead being excreted in urine. It can be found in a range of foods, including poultry, vegetables, and bread. Some of its key functions include aiding the use and storage of energy from protein and carbohydrates consumed in the diet and involvement in the formation of haemoglobin.


Acetyl-L-carnitine is an amino acid that is found in the human body and helps with energy production. It is found in greatest quantities in beef, but is also present in milk, poultry, and cheese, amongst other food products. It is however not essential that people obtain the nutrient from these sources, since the body produces enough for general health. The ingredient is thought to have a variety of health benefits, ranging from the treatment of cancer to improving athletic performance.


L-theanine is another amino acid, this time found in tea. It is thought to act very similarly to glutamate – an amino acid that occurs naturally in the brain. The consumption of L-theanine has been suggested to have an impact on brain function, potentially having a relaxing effect (not accompanied by the related effect of drowiness). The ingredient is often added to health supplements in an attempt to treat a number of conditions, including, for example, anxiety and high blood pressure.


Caffeine is a well-known stimulant that occurs in common products such as tea, coffee and chocolate. It affects the central nervous system, impacting the body’s metabolism and providing an energy-enhancing effect. This ingredient is also commonly used in supplements; though mainly used for increasing alertness, caffeine is also used to treat headaches, asthma, and type II diabetes, to name just a few conditions. The substance is however associated with a long list of side effects, which can affect some people more than others.

Rhodiola Rosea Extract

Said to be found in parts of Europe, Asia, and Alaska, Rhodiola rosea is the name of a plant, the root of which is sometimes used in health supplements. Though there is very little reliable scientific evidence in support of its potential to aid any health conditions, the ingredient has been said to improve disorders such as depression and heart problems (e.g. irregular heartbeat and high cholesterol). It has also been advertised as having the potential to increase energy and mental capacity.

Bacopa Monnieri Extract

Bacopa monnieri is the name of another plant, otherwise known as brahmi, found all over the world and commonly used in Indian medicine. The extract is thought to contain chemicals that impact the brain, potentially impacting functions such as memory and learning. It is used as a supplement to treat a range of brain conditions, including anxiety and Alzheimer’s disease, as well as some physical conditions such as hoarseness and joint pain. Others claim that the substance can boost sexual performance.

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Clinical Studies

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There do not appear to have been any clinical trials undertaken on the product as a whole. Some studies have been performed on the ingredients, both to look at their effectiveness in improving brain function and in aspects associated with weight loss; we will only focus on any weight loss potential of ingredients here.

A clinical study is a method used by scientists to determine whether or not a product or ingredient has the properties that it is claimed to have. These studies are usually reliable, since experts review them before they are published in journals online, but some are of better quality than others.

Clinical Studies On Each Ingredient

Clinical Studies on Acetyl-L-Carnitine

There is no strong evidence that links acetyl-L-carnitine to weight loss. A couple of studies have been undertaken to address the claims that the ingredient will help people to lose weight. One study was performed on rats in 2002. The study investigated whether or not L-carnitine supplementation could influence weight loss or body composition when combined with a low-calorie diet. Thirty-six rats were divided into a treatment group, which received L-carnitine supplementation, and a control group, which did not receive supplementation, for 23 days. Results showed no significant differences in weight or fat lost between the two groups, suggesting that L-carnitine has no significant impact on weight loss.

Another study looked at the effects of L-carnitine on weight loss in humans. For this trial, 36 overweight, premenopausal women were randomly assigned to either a L-carnitine group or a placebo group. The participants took their designated treatment for eight weeks alongside regular exercise. Twenty-eight subjects completed the trial and, as with the previous study, the results did not indicate that L-carnitine has any significant effect on weight loss or body composition.

Clinical Studies on L-Theanine

L-theanine is found in green tea – an ingredient that commonly features in weight loss products and does have some evidence (though limited) to suggest that it could have a slight effect on weight loss. This effect might however be due to the catechins and other components of green tea, which are not present in this supplement. Few studies have tested the potential weight loss effects of L-theanine alone. A 2004 article published in the journal ‘in vivo’ was performed in an attempt to identify which components of green tea have an impact on body weight. The trial was performed using mice and methods are not entirely clear. It is stated in the results that caffeine and theanine (both of which are present in this supplement) were responsible for suppressing weight and fat gain. This result is, however, not backed by any higher-quality studies.

Studies have, on the other hand, looked at the potential effect of L-theanine on mental health, which could have a secondary effect on body weight in some individuals. A small, low-quality study using 12 human subjects was done to look at the effect on L-theanine on psychological and physiological stress. The authors of this trial reported anti-stress effects of L-theanine taken orally.

Clinical Studies on Caffeine

Of all the ingredients in Addium, caffeine is best studied with regards to its potential effects on weight loss. One study used a sample of lean and postobese human participants to test the influence of caffeine on thermogenesis (fat burning) and energy expenditure (metabolism boosting). The results of this trial showed that caffeine, when supplemented at doses commonly consumed, can have a significant impact on energy balance and might promote thermogenesis. A similar study reported that caffeine can cause increased metabolism in normal weight and obese individuals, but that fat oxidation is only boosted in normal weight subjects.

A third study looked at the potential appetite-suppressing effects of caffeine, as opposed to fat burning or metabolism boosting impacts. Here, 16 women and 17 men took part in three trials per day involving the consumption of varying amounts of caffeine with breakfast. Consumption at a buffet-style lunch was then recorded a little later in the day. Results indicated that caffeine could significantly reduce hunger in men and energy intake in women, suggesting that the substance could suppress appetite in men and energy intake in female consumers.

Although there are more studies suggesting that caffeine can aid weight loss than there are for other ingredients in this product, it is still important to note that caffeine has not been conclusively proven to act as a significant aid to weight loss.

Clinical Studies on Rhodiola Rosea Extract

Rhodiola has not been well-tested for any potential weight loss effects. A study published in 2013 investigated the impacts of Rhodiola on weight loss in rats when combined with Cirtus aurantium. Results were positive, suggesting that this combination could induce fat loss; however, these effects might well have been the result of the Citrus aurantium – an ingredient that might cause weight loss but has been deemed unsafe for use. Citrus aurantium is not present in this supplement and there is no way of saying whether Rhodiola rosea was responsible for the results of this trial.

A few more studies have investigated the potential impact of Rhodiola on mental wellbeing. In one such study published in 2012, subjects with symptoms of life stress were given rhodeola rosea extract for four weeks. One hundred and one participants took part in the trial, but there was no control group, limiting the reliability of its results. The authors of this paper reported significant improvements in stress symptoms with Rhodiola supplementation.

A randomised, double-blind, placebo-controlled trial was published in Phytomedicine in 2003. This study used 161 young participants (aged 19-21) to test the effects of Rhodiola rosea on mental capacity in a situation of fatigue and stress. The results highlighted an anti-fatigue effect of Rhodiola rosea, indicating that the substance might help to reduce tiredness.

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Addium Side Effects

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There is no mention of any side effects on the Amazon website that sells Addium. It is important to remember that there are side effects associated with all supplements and Addium is no exception. The disclaimer on the seller page also states that the product you receive might contain different and/or more ingredients than are shown on the website. It is very important that you read any information (e.g. how to take, who shouldn’t take, and full ingredients list) provided with the product to minimise the risk of unpleasant side effects. The ingredients in Addium are associated with some side effects; these are described in more detail below.

Side Effects Associated With Each Ingredient

Side Effects associated with Vitamin B6

Vitamin B6 has not been associated with any side effects when taken in quantities that are usually consumed in foods. The product label states that there is 10mg of vitamin B6 in Addium; this should be safe since the tolerable upper intake level for men and women (including pregnant and lactating women) is 100mg. Chronic administration of vitamin B6 over long time periods can cause loss of control of body movement as well as skin lesions, increased sensitivity to sunlight, and gastro-intestinal problems. Again, these are unlikley to occur if this supplement is taken alongside a healthy diet.

Side Effects associated with Acetyl-L-Carnitine

Since L-carnitine is naturally produced in the body, it is unlikely to cause any side effects when consumed in sensible quantities. Over-consumption of L-carnitine can however cause some problems. These include: nausea, vomiting, diarrhoea, upset stomach, and heartburn. Consuming large amounts might also induce seizures and cause urine, breath, and sweat to have an unpleasant odour. It may increase symptoms of hypothyroidism. The precise quantity of L-carnitine present in Addium is not disclosed.

Side Effects associated with L-Theanine

L-theanine, the amino acid found in green tea, has also not been associated with any severe side effects. When taken as a supplement once a week for up to three weeks, it is thought to be safe; side effects that might occur as a result of consumption in the long term however, have not been studied. Because of a lack of information on L-theanine supplementation, it is recommended that pregnant or breastfeeding women avoid supplementation with the ingredient. There is suggestion that theanine might interact with certain medications; consult a doctor before taking L-theanine supplements if you are taking medicines for high blood pressure or stimulants.

Side Effects associated with Caffeine

Caffeine is a commonly consumed substance that can affect people to different levels. The precise dosage of caffeine in Addium is not disclosed and so if you are sensitive to caffeine, we would recommend that you avoid this product. Caffeine can cause side effects such as headaches, nausea, heart burn, jitteriness, insomnia/inability to fall asleep, increased heart rate and blood pressure, irregular heart beat, nervousness, dry mouth, anxiety, and dehydration. Moreover, taking caffeine on a regular basis for long periods of time can result in a dependence on the substance which, in turn, can cause withdrawal symptoms such as headaches, muscle aches, depression, and irritability. The substance can worsen cardiovascular problems and anxiety. Large amounts of caffeine should not be consumed whilst pregnant; consult a doctor before taking this product if you are pregnant or breastfeeding.

Side Effects associated with Rhodiola Rosea Extract

Rhodiola rosea is fairly understudied and so all potential side effects might not yet be known. For this reason, we recommend that all customers consult a doctor before taking the ingredient, particularly if you have any pre-existing health conditions. Rhodiola is believed to be safe for consumption for up to 10 weeks, but its safety in the long run has not been studied. As such, we would recommend avoiding this ingredient if you are pregnant or breastfeeding.

Side Effects associated with Bacopa Monnieri Extract

As with Rhodiola, Bacopa monnieri extract has not been subject of much clinical testing and as a result, potential side effects associated with the ingredient might not yet be recorded. WebMD indicates that the substance could be safe for consumption for up to 12 weeks and lists some potential side effects, including: stomach pain, nausea, increased bowel movements, fatigue, and dry mouth. It is thought that Bacopa might reduce the heart rate; if you have any history of cardiovascular or blood-related problems, we recommend consulting a doctor before use. Similarly, if you have a history of gastro-intestinal problem (including ulcers or blockages), lung conditions, thyroid problems, or urinary tract obstructions, you should not take this ingredient without consulting a medical professional.

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How To Use

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On the ingredients list displayed on the back of the bottle, as imaged on the Amazon website, it is written that a serving size is two capsules. There are, however, no directions with regards to how to take the product, how often to take it, or when to take it.

It is stated in the disclaimer that you should always read warnings and directions before use. It is also mentioned that the product has not been evaluated by the FDA and is not intended to be used to treat any health problems. Finally, it is stated that the manufacturer might add or remove ingredients, making the ingredients list different on the actual product to that displayed on the retail website.

All potential users should contact a doctor before using this product, particularly since the quantities of all ingredients are not disclosed. You should not use this product if you are pregnant, breastfeeding, or under the age of 18. We would not recommend use of this supplement if you are sensitive to caffeine, or if you have a history of cardiovascular problems or mental illness, including anxiety and depression. Similarly, do not use if you have a bleeding disorder, diabetes, epilepsy, glaucoma, irritable bowel syndrome, or osteoporosis.

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Who Makes It

The product does not appear to have an official website, and so it is not clear who makes the supplement. This means that there is no way of knowing how reputable the brand is, whether or not they make any other products, who manufactures the product, and whether or not there are any manufacturing certificates associated with Addium.

The only place that we can find a retailer for Addium is on the Amazon website. Here, the supplement is sold by a seller under the name ‘The Very Best’, who sells a selection of other health-related products and toys. The product is not actually manufactured by ‘The Very Best’ – just sold by them. It is shown that Addium is made by ‘Addium’, but no further information is provided on the company behind the product.

Due to the lack of official website or indeed any information on the manufacturer behind Addium, there is no way of contacting the company; no telephone numbers, email addresses, or postal addresses are provided by the seller for the manufacturer. It is possible to ask questions about the product via the Amazon site, but there is no guarantee that these will be answered by the seller, let alone by the manufacturer. There are no money-back guarantees or multi-buy offers.

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Where To Buy Addium


Having searched the web for purchasing options, we could only find one place that sells Addium, and this is via the international online retailer, Amazon. The product does not appear to be available in high street stores or any well-known online health retailers. On Amazon, Addium (titled ‘Addium – Limitless Pill – the Most Powerful Brain Enhancer in the World’) is sold by a seller called ‘The Very Best’; no other sellers appear to stock the product.

The product is available on the USA Amazon site, where it is sold for $79.98 (around £65). We could not find the supplement on the UK Amazon site. The advertisement states that the price is for 60 pills. The pictures shown on the product page differ; the image of the front of the Addium container states that it contains 60 capsules, whilst the image of the back of the container states that it contains 30.

It mentions that a serving size is two capsules, but we do not know how long one container will last since guidelines on when to take the product and how often to take it are not available. Standard shipping is free (and takes around 1-2 weeks), but there may be additional charges and delays for international shipping options.

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Does Addium Meet our Approved Criteria

Money-back-guarantee: No, there does not appear to be a 30-day money-back guarantee.

One-off payment: Yes, the payment seems to be one-off via the Amazon retailer; an official product website cannot be found

Manufacturing Standard: No, there is no mention of any manufacturing standard certification

Accompanying Diet Plan: No, there is no mention of a diet plan with this product

Ingredients and quantities disclosed: Yes, the ingredients list is provided, but the specific quantities of each individual ingredient are not available.

Company contact details readily available: No, the retailer can be contacted via Amazon, but it is not clear what company manufactures the product.

Addium does not meet our ‘Approved’ criteria because it fails to provide a moneyback guarantee.

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Overall Verdict

Addium is a supplement that is advertised principally as a brain enhancer. It contains a selection of ingredients that are thought to increase mood and focus, some of which have been associated with weight loss in the past. The product does not have an official website and so lots of important information, including contact details, manufacturing standards, potential side effects and people who shouldn’t take the product, is unavailable to the consumer. The product is sold on Amazon with free shipping in America, but is not available on the UK site. Some ingredients have been studied for potential mood-enhancing effects, but none have strong clinical evidence supporting their claimed weight loss effects.

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