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Lipodrene

Lipodrene claims to be a pharmaceutical-standard weight loss formula that focuses on shedding fat from typically stubborn areas, including the hips, thighs and buttocks. It promotes itself as a scientifically researched fat-burner for people of any weight, although it’s unclear on the quantity-value of all its ingredients.

lipodrene

Lipodrene Pros
  • Claims to target a variety of different weight management areas
Lipodrene Cons
  • Contains ephedra, which is a banned substance
  • Only states the quantity value for certain ingredients

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Lipodrene Review

Lipodrene contains quite a wide selection of ingredients to achieve its claim of being an effective fat-burner for people of any size. Its manufacturer alleges that a great deal of clinical testing, medical data and scientific research was involved when creating Lipodrene, which can apparently work as a diuretic, energy enhancer and appetite suppressant. It also states it can actively combat particularly difficult areas of fat, while remaining a safe and sustainable supplement. However, information about the quantity of all the ingredients is vague and it contains ephedra, which has been banned in the USA by the Food and Drug Agency since 2004.

Lipodrene Claimed weight loss benefits

Lipodrene claims to tackle an admirable array of weight management areas. These include: burning fat, quelling appetites, boosting energy, enhancing metabolism and regulating the rate of thermogenesis. Lipodrene allegedly focuses on stimulating the disposal of fat while helping to prevent further fat storage, which is seemingly how it manages to reduce weight from hips, thighs and buttocks. However, none of Lipodrene’s statements have been examined by the FDA nor has it been subjected to clinical testing.

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How Lipodrene Works

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The NutraSource website devotes an entire page to describing how Lipodrene works to benefit weight management, although the scientific support to back these claims is sketchy. Basically, this product aims to target fat, energy, appetite, metabolism and thermogenesis. It supposedly tackles stubborn fat areas in the hip, thigh and buttock areas, while boosting the user’s energy for physical exercise and improving the thermogenic and metabolic rates to quicken the process of calorie expenditure. The product also suggests a skill of suppressing the user’s appetite, although this is not promoted as much as the other claims and none of the assertions appear verified by reputable trials.

Ephedra
Ephedra is popularly used for weight loss due to its apparent ability for stimulating the brain, raising heart rates, narrowing blood vessels and expanding bronchial tubes for easier breathing. Its main alkaloids are ephedrine and pseudoephedrine, which provide the stimulating ability of the ephedra plant and supposedly boost thermogenesis and raise metabolic rates, while simultaneously providing a mental and physical exertion of energy.

Caffeine Anhydrous
Caffeine anhydrous is a more potent form of caffeine, but it fundamentally functions in the same way. Similar to ephedra and often used in conjunction with it, caffeine reportedly triggers motivation in the brain, heart, muscles and central nervous system. This allegedly allows it to boost mental and physical energy levels to a certain extent and perhaps increase the metabolic rate of the user in the process.

Acacia Rigidula
Acacia rigidula contains chemical compounds that can apparently enhance a biological function call lipolysis, as well as reduce the appetite of the user. It manages this by stimulating certain beta-receptors, which can influence the metabolic and thermogenic rates while decreasing feeling of hunger. However, there are no verifiable clinical studies to support these claims.

Synephrine
Commonly, synephrine is used as a substitute to ephedra due to its functional likeness but generally higher safety level. Synephrine is the main stimulant of bitter orange and mainly works by increasing the heart rate, boosting blood pressure and constricting blood vessels. Synephrine reportedly increases energy levels by triggering alpha-adrenergic and beta-adrenergic receptors. These spark energy and should enhance exercise endurance. Synephrine alkaloids are also reported to slow the movement of the stomach, which may help suppress the appetite. However, this relies on the concentration in the dosage, which at 25mg, may not be high enough in Lipodrene.

Theobromine
The effects of ingesting theobromine is similar to caffeine, although weaker. It has stimulating abilities and works as a diuretic, which are reported to assist weight loss to a certain degree. Theobromine can allegedly also relax muscles in the lungs for easier breathing when exercising that may help the user work out for longer periods, similar to fellow stimulant ephedra. However, there may not be enough in Lipodrene to cause this outcome and the true weight loss ability of theobromine has not been proven.

Green Tea
Green tea contains a concoction of caffeine, catechins and antioxidants that supposedly help speed up the metabolism so it burns calories at a quicker rate than normal. The catechins are reported to lower both cholesterol and blood pressure, as well as prevent the deterioration of nerve cells. However, there appears to be more evidence for its general health benefits than there is for its weight loss skill and many trials conducted on it were short-term or used animal subjects.

Hoodia
Hoodia has limited apparent weight management ability. It reportedly contains a chemical similar to glucose that signals a sense of satiety to the brain, which is received by the hypothalamus and alters the brain’s sense of hunger. However, there’s no scientific evidence to support the theory that it hinders hunger pangs enough for significant weight loss and Lipodrene doesn’t state how much hoodia is in each capsule.

Yohimbe
Yohimbe is commonly distributed as a herbal aphrodisiac and is used for the treatment of sexual problems, particularly erectile dysfunction. However, its capability in this area could also boost weight loss due to its skill of raising the heart rate and increasing blood circulation, which may be useful for supplying a surge of physical energy for exercising.

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Key Ingredients

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There’s an extensive list of ingredients in Lipodrene, including many that are popularly used in other diet pills or even individually. This lends some support to the weight loss potential of the Lipodrene formula. However, the inclusion of ephedra, which stands at 25mg per tablet, may worry some users. The FDA opted to ban this ingredient due to its dangerous side effects, but it remains popular because of its supposed weight loss ability. Considering the quantity value of every element is not detailed, it’s also quite tough to establish how this concoction of stimulants will react with ephedra.

Ephedra
Ephedra, from the plant Ephedra sinica, has been a part of Chinese medicine for thousands of years and can be used to treat respiratory ailments including asthma and nasal congestion. It’s often confused with ephedrine, which is actually one of Ephedra sinica’s primary chemical components along with pseudoephedrine. Ephedra is mainly used to stimulate the brain for cognitive readiness, as well as supposedly giving the user an energy surge for physical endurance due to its motivation of the heart and central nervous system. However, ephedra-based supplements are currently banned in the USA due to its health risks and fatalities of past users, which may

Caffeine Anhydrous
The difference between caffeine and caffeine anhydrous is the quantity of fluid, as caffeine anhydrous has an insignificant amount of water content. Caffeine anhydrous is often stronger than normal caffeine and so its stimulating effect can be more powerful and even dangerous. Caffeine originates from the South American coffee plant Coffea arabica. Standard caffeine is now enjoyed internationally in tea, coffee and chocolate, but caffeine anhydrous is usually more prevalent in supplements. Caffeine is a psychological stimulant that has been known to boost the heart rate, alter the mood and influence the energy level of its user, although this differs depending on tolerance and dosage.

Acacia Rigidula
Acacia rigidula, also known as Vachellia rigidula, is a type of shrub native to North America. Studies have shown that it contains at least 40 alkaloids and several amphetamines. High amounts of tyramine, phenethylamine and N-methyltyramine were reported to have been found in a sample, all of which are psychoactive compounds that influence brain function. The 125mg of phenylethylamine alkaloids in Lipodrene come from acacia rigidula and function as neurotransmitters. They release dopamine and norepinephrine, both of which are key to cognitive alertness and can enhance blood flow to benefit physical performance. However, studies into the safety or advantages of acacia rigidula have not been verified.

Synephrine
Synephrine is a plant alkaloid derived from the citrus aurantium or bitter orange tree. Citrus aurantium contains different chemicals that affect the nervous system, as well as apparently narrowing blood vessels, raising levels of hypertension and increasing heart rates. Synephrine reportedly boosts energy by triggering alpha-adrenergic and beta-adrenergic receptors, which assist physical vitality. It has also been reported to slow gastric movement, which may support its use as an appetite suppressant. However, there have been no clinical trials conducted on synephrine and it’s unknown whether the 25mg of it in each tablet of Lipodrene will be enough for a weight loss outcome.

Theobromine
Theobromine was once known as xantheose and is a bitter alkaloid commonly found in chocolate, tea leaves and the kola nut. It was discovered in cacao beans by a Russian chemist in 1841 and is now the primary alkaloid in cocoa and chocolate. Theobromine doesn’t actually contain bromine, which is a halogen element, and it comes in the form of a water-soluble powder. Its effect on the nervous system is generally likened to caffeine, but weaker. Some attributes that are often considered beneficial include its ability to widen blood vessels, behave as a diuretic and stimulate tissue. However, there’s little research to validate it as a weight loss aide.

Green Tea
Green tea is native to China and has played a pivotal role in its medicine for centuries. Green tea is popular as a general health aide due to the assortment of lipids, catechins, minerals and amino acids it contains, which may be why it is now commonly consumed throughout Asia. It is used as treatment for both minor and major illnesses and there’s growing scientific speculation that it could help prevent or even cure serious diseases such as: cancer, hyperlipidemia and cardiovascular disease. However, the FDA has not sanctioned green tea and none of these claims have been proven via scientific testing yet.

Hoodia
Hoodia, or Hoodia gordonii, is part of the Apocynaceae family and native to Southern Africa, where it is also called “Bushman’s Hat”. It has long been used by people in the Namib Desert as a survival tactic because it supposedly has the ability to suppress the appetite. This is beneficial in this harsh environment, but the weight loss potential of hoodia was soon recognised and it is now sold internationally. Many of its species are protected in their natural habitat due to its endangered classification, although many are also grown as garden plants. The significance of its skill at kerbing the appetite is disputed and remains unproven.

Yohimbe
Yohimbe, also called yohimbine, is an indole alkaloid taken from the bark of the Pausinystalia johimbe plant native to Central Africa. It’s perhaps most frequently administered to stimulate the blood and treat impotence in men, as well as female sexual problems. It’s currently only provided on prescription under brands including Yocon and Testomar, and has also been known to boost blood pressure and cure xerostomia (dry mouth). However, yohimbe lacks serious study in regards to its use as a weight loss aide and many experts doubt its ability in this field.

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Clinical Studies

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Clinical studies and thorough scientific research are highly valued in the supplement industry, if they can be attributed to a particular product. The NutraSource website claims that clinical trials of Lipodrene are testament to its success, particularly in regards to its fat-burning ability. It also states that medical journals and scientific data further support the capability of Lipodrene for enhancing the metabolism and shedding fat. However, no evidence of these experiments, nor the scientific data itself, is available to read. This suggests users should treat the company’s claims with caution, although this doesn’t mean that the claims are completely untrue.

Ephedra
Since the safety of ephedra has been brought into disrepute, one study looks at its effect on cardiovascular function when given alongside caffeine. A total of 27 healthy, but overweight, adults were given either the ephedra and caffeine supplement or a placebo. The results showed no difference in the heart rate, blood pressure or cardiovascular physiology between the supplement and the placebo, despite expectations to the contrary. This suggest that ephedra may not be as dangerous as many suggest, but far longer trials are needed.

Caffeine Anhydrous
One study looked at how caffeine can influence energy and metabolic rates. A total of eight, trained cyclist were used in this trial, with each drinking either: caffeine, instant coffee, decaffeinated coffee or a placebo supplement an hour prior to cycling. Results showed that those consuming caffeine or instant coffee were approximately 5% quicker than the rest. This may suggest that caffeine can enhance physical performance, but the difference is not substantial.

Acacia Rigidula
One study examined the weight possibility of caffeine anhydrous and acacia rigidula on 27 men. Each participant took either: 300mg of caffeine, 250mg of acacia rigidula, Fastin XR weight loss drug or a placebo and were monitored throughout. The outcome showed that acacia rigidula produced greater oxygen consumption than caffeine and both showed a far higher metabolic rate. Neither was as adept at oxygen consumption or metabolic rate as Fastin XR, but this suggests that acacia rigidula may slightly benefit weight loss. Acacia rigidula yields the blend of phenylethylamine alkaloids and this study examined ten people who were given three capsules of either the phenylethylamine blend or a placebo on two separate sessions. The findings suggest that those ingesting the phenylethylamine blend experienced a significantly higher metabolism and thermogenic rate than the placebo group. This lends some support to the capability of Lipodrene’s phenylethylamine mix.

Synephrine
Synephrine is the chief protoalkaloid of citrus aurantium. One trial looked at the effects of it on mood, blood pressure, heart rate and metabolism, which were checked at the beginning of the trial and 75 minutes after supplement consumption. Some of the participants were given a mix of synephrine and other elements, but those taking only synephrine showed a 65 kcal rise in resting metabolic rate (RMR) compared to placebo users. However, combining naringin with synephrine showed the best RMR of 129 kcal, although there was never a change in heart rate or blood pressure. This implies that Lipodrene’s combination of synephrine and naringin may be a shrewd strategy.

Theobromine
One test looked at the mood effect of caffeine and theobromine on 80 healthy subjects. A different quantity of theobromine (250mg, 500mg or 1000mg) was administered to the participants with the results showing that caffeine caused increased mental alertness. Interestingly, lower levels of theobromine tended to create a positive mood, whereas the 1000mg dose incited negative emotions. More research is needed, but this indicates that certain amounts of theobromine may have a positive effect on the user’s mood.

Green Tea
Random doses of green tea were given to subjects in one trial to find out whether the element influenced fat oxidation and energy expenditure. It took place over 24 hours and involved ten men who were given either green tea extract, caffeine or a placebo for breakfast, lunch and dinner. Findings suggest that green tea increased thermogenesis, boosted physical energy and enhanced fat oxidation more than caffeine and the placebo. Unfortunately, there may not be enough green tea in Lipodrene to cause these positive effects.

Hoodia
Two samples of Hoodia gordonii were given to rats in one investigation to establish their appetite suppressing ability over eight days. The body mass and food intake of the rats were monitored and the results showed that those given the hoodia compound showed a decrease in both weight and food consumption. However, its effect in humans may differ.

Yohimbe
The effect of yohimbe on body mass and physical performance of football players was examined in one trial. Half the players were given a tablet of 10mg yohimbine and the rest took a placebo, but everyone had two tablets a day for three weeks. The results showed that those taking yohimbine had a much lower body fat percentage, although no difference in exercise performance was noticed. However, far large studies must be conducted to take yohmbine seriously as a weight loss aide.

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Results

Weight Loss Power: 60/100

The combination of a wide range of stimulating ingredients implies that Lipodrene should be able to deliver a potent kick-start to a weight loss regime. It focuses on targeting several areas of weight management, as opposed to tackling one or two, which could also suggest a more effective supplement. However, there are no clinical studies to support either its power or success as a weight loss aide.
Speed of results: 60/100

There are such a vast variety of stimulants in Lipodrene that it’s highly likely it will provide weight loss relatively rapidly. The inclusion of ephedra, although possibly risky, should speed up the rate of weight reduction and it seems probable that fellow ingredients synephrine, green tea and caffeine anhydrous, will complement its pace. However, this is merely speculation based on past research of the ingredients in a different dosage quantity.
Appetite Suppression: 50/100

Studies have implied that many stimulants, including those that are contained in Lipodrene, have the ability to quell appetites. It may even be an unexpected outcome of the user’s stimulation to exercise and get fit, since stimulants usually boost mental readiness and motivate energy levels. However, only hoodia truly focuses on suppressing hunger out of all the elements and it’s unclear how much of it is actually in Lipodrene.
Long Term Results: 50/100

Since there are no long-term studies on past users of Lipodrene, it’s difficult to attribute a high rating to it. A stimulant usually only delivers a surge of energy or burst of high metabolic rates, so the longevity of Lipodrene most likely depends on the motivation of the user. It may rely on the consumer’s dedication to acting on any stimulation they experience than the supplement itself.
Safety: 20/100

Lipodrene contains a banned ingredient that has gained notoriety for its dangerous and harmful potential. Ephedra continues to appear in supplements despite the known risks and there’s no indication of how it may react with Lipodrene’s other ingredients. Ephedra has caused death in some of its users, but arguably the 25mg included in each Lipodrene capsule may not cause safety issues.
Value for money: 60/100

The safety risks and lack of clinical studies are two major factors in rating Lipodrene’s value and should be seriously considered before purchasing. There are many other products on the market that contain similar elements for a similar price. However, Lipodrene offers quite a long list of popular weight loss ingredients for its price, as often manufacturer concentrate on perhaps four or five. This works in its favour, but the negative potential of ephedra and lack of ingredient quantities diminish the value of Lipodrene.

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Lipodrene Side Effects

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There is often a wide range of potentially harmful side effects to be aware of when taking any medication or supplement, particularly when they contain several different elements. Lipodrene’s ingredient list is impressively long, although this is not necessarily uncommon in the weight loss industry. However many of its ingredients, such as caffeine and green tea extract, are stimulants and are renowned for causing adverse side effects. Often these are minor and only experienced if the user has a particularly low tolerance or ingests too much. Unfortunately, the quantity of each ingredient in Lipodrene is unclear, which makes it more difficult to evaluate its true risk potential.

Ephedra
Ephedra, of which there is 25mg per capsule in Lipodrene, is probably the most harmful of all its ingredients. It’s linked to a plethora of health problems that range from uncomfortable to potentially lethal. These include: strokes, seizures, headaches, sickness, irritability, restlessness, irregular heartbeats, high blood pressure, muscle disorders and heart attacks. Studies into ephedra aren’t clear on how much is needed to cause serious side effects, although this will possibly depend on the tolerance and health of the user. Ephedra is a banned substance in the USA and should be taken with extreme caution.

Caffeine Anhydrous
It’s important to remember that caffeine anhydrous is a more potent form of caffeine. Consequently, it can cause quite a variety of adverse side effects such as: diarrhoea, nausea, shaking, headaches, dehydration, dizziness, sleep problems and rapid heartbeats. Substantially large amounts of caffeine anhydrous may cause confusion, convulsions and gastric pain, although the amount in Lipodrene is unlikely to incite such severe side effects.

Acacia Rigidula
Acacia rigidula contains many psychoactive compounds which can be harmful to the functioning of the brain, if abused. However, it’s unlikely that there’s enough to cause damage in Lipodrene. Other possible side effects of acacia rigidula are: headaches, heartburn, nausea and constipation, although there are few reports of people suffering from these issues. Similarly, the phenylethylamine blend may cause side effects commonly relating to stimulants, such as headaches, nausea and sleeplessness. However, there’s not necessarily enough in Lipodrene’s dosage to cause these.

Synephrine
Synephrine can cause some adverse side effects in particularly large doses such as: headaches, anxiety, rapid heartbeats and even angina pectoris, though this is rare. Consequently, people with cardiovascular diseases, high blood pressure and glaucoma should avoid any supplements containing it. Synephrine may also cause harmful interference if used with other medication, stimulants and anaesthetics.

Theobromine
Theobromine is quite safe to ingest, although can be toxic if exceptionally large doses are eaten. Theobromine is essentially a stimulant and large amounts can contribute towards headaches, nausea, sleeplessness, increased urination, digestive discomfort and even heart palpitations. However, Lipodrene isn’t likely to contain enough for these negative outcomes.

Green Tea
Harmful effects of green tea can include: heartburn, headaches, rapid heartbeats or a gastric discomfort and it should not be taken by people with heart problems or hypertension. The catechins in green tea have also been blamed for causing hepatotoxicity, which is chemical-driven liver damage. However, most dangerous outcomes are experienced only after excessive amounts of green tea.

Hoodia
Hoodia is generally a safe ingredient, although some side effects include vomiting, stomach cramps and elevated blood pressure. Those suffering from diabetes should also avoid hoodia, as it can influence the brain’s perception of glucose levels. Patients using blood-thinning medication such as aspirin or warfarin should also not consume hoodia, as it is reported to contribute towards thinning the blood.

Yohimbe
Yohimbe may cause minor ailments including tremors, anxiety, agitation, headaches and nausea, although most likely only as a result of a large intake. However, more serious ailments of yohimbine consumption are: seizure, kidney failure, heart attack or irregular heart beat, but the quantity value to induce these outcomes is unestablished.

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How To Use

Lipodrene’s home website gives no information describing how to use the product for the safest and most successful outcome. However, there is some general advice given on the bottle. It states that the user should take one or two tablets in the morning, followed by one tablet after lunch. However, there’s no indication whether these should be taken with or without food. It also advises that the user should not take more than four tablets in one day. It’s suggested that the user consult with a doctor before starting a course of Lipodrene, as it can raise blood pressure and interfere with other medication. Pregnant women, nursing mothers and people under the age of 18 are also warned off the product.

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Who Makes Lipodrene

Lipodrene is produced and distributed by NutraSource, which claims to offer low-priced and high-quality health supplements. Nutrasource was founded in 2003 and trades completely online, apparently to eliminate the expense of physical stores, and all of its orders are shipped from its warehouse in Idaho, USA. NutraSource calls itself a ‘nutraceutical’ company, which is a relatively modern word coined from ‘nutritional’ and ‘pharmaceutical’. It’s popularly used to describe herbal and dietary supplements and attributed to products providing health or medical benefits, although there’s no distinct definition. NutraSource have a wide variety of other products on offer that appear to fall under one of five categories: weight loss, health care, pre-workout, male performance and muscle strength. It also offers a 60-day money back guarantee, but there are many requirements that must be met by the customer for refunds to be honoured. This includes a term stating the product must be returned unopened for a reimbursement to be approved, which casts slight doubt on the fidelity of the company. Generally, the product appears to have worked for many customers since its release. However, there have been some registered complaints regarding the delivery speed, but the amount isn’t overwhelming.

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Where To Buy

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Lipodrene is available via a dedicated website from NutraSource, although not in any high street shops. Buyers can purchase one bottle of Lipodrene for $39.95 (£26.02); two bottles for $73.90 (£48.21); three bottles for $110.85 (£72.32) or six bottles for $185.70 (£121.15), but international shipping is separately charged. Astro Nutrition and Ephedra.co.uk also sell one bottle for £37.99; £71.98 for two bottles or £101.97 for three, with different shipping options available. However, delivery times will probably not be exceptionally quick since the product must be shipped from the US. Unfortunately the product isn’t available from Amazon, which usually has a good standing as a distributor. It can be bought from the American eBay site for approximately $24.79 (£16.17), although this does not include posting and packaging costs and there are many different versions of it on offer, which is confusing.

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Overall Verdict

There are many arguments for and against Lipodrene as a weight loss aide. It certainly contains many ingredients that are popularly used in other high-selling products and research into several of its elements suggest they may complement and assist each other quite efficiently. However, the presence of ephedra is worrying because of its relation to so many adverse side effects. The dubious money back guarantee offered by the manufacturer and lack of clarity regarding the ingredients’ quantities may also be contentious points, although the company encouragingly appears to make many other health products and Lipodrene itself continues to receive reasonably high-rated reviews from customers.

Overall: 60/100

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