Xenamine, produced by small-time manufacturer InnerVital, promises to use ‘thermogenics and lipotropics’ to help users burn fat faster than any other supplement. Conclusive evidence is not available to support this bold claim.
Below we have reviewed Xenamine against our review criteria to help consumers make an informed decision.
- Contains some ingredients that have been studied
- No reported side-effects or media scandals and few complaints against the manufacturer
- Mention of a money-back guarantee
- Not been proven to aid weight loss
- High level of caffeine can be dangerous when taken in the long-term, with potential unpleasant short-term effects also
- Very little information given about the company
This product is alleged to work as a metabolism booster and appetite suppressant. Xenamine unfortunately has no user reviews online and a lack of information provided by InnerVital, but some of the ingredients have been shown to have fat-burning properties in preliminary studies.
Claimed weight loss benefits
The main website claims Xenamine uses ‘thermogenesis and lipotropics’ to aid in weight loss. Thermogenesis is the process of generating heat; in biology, the term usually applies to metabolic reactions which create heat in the body. Xenamine’s website makes it clear that the ‘thermogenic properties’ of the ingredients should cause the body to burn more fat and increase available energy – both of which are properties of increased metabolic rate. They also claim that the product can cause appetite suppression.
How Xenamine Works
The ‘How it works’ page claims Xenamine uses ‘two key principles; thermogenesis and lipotropics’ to enhance weight loss; xenamine supposedly ‘burns away fat deposits and converts them to energy’. However, there are some inaccurate points made; for example, Xenamine attributes an increase in energy to ‘increased blood flow to the muscles’, and they claim that the thermogenic properties decrease hunger – two things that are not thought to be linked.
Xenamine also claims to contain ‘lipotropic compounds’ that ‘catalyse the breakdown of fat during metabolism’: methionine, choline, inositol and betaine. These allegedly speed up metabolism and fat metabolism, prevent fat build-up in the liver and help with the digestion of fat-soluble nutrients.
There are no independent studies on Xenamine provided by the company or available online, so studies of the ingredients must be used instead.
Chromium (amino acid chelate)
Little information is available about this form of chromium online, although it could refer to chromium picolinate, a fusion of chromium and picolinic acid. Chromium itself is a metal that has no verified biological role, but there is debate whether ions of chromium can cause increased metabolic rate. Chromium is suspected to cause damage to the kidneys, blood cells and liver through oxidation reactions when in large concentrations, and certain chromium compounds are suspected carcinogens. Some studies have revealed effects on glucose metabolism in diabetic patients, but review articles of many such studies conclude that chromium had no effect in non-diabetic patients. This suggests chromium may be necessary in small amounts for glucose metabolism, but that increasing chromium levels may not affect metabolism.
Caffeine is a known supplement, believed to work by increasing metabolic rate whilst reducing mental and physical fatigue. Caffeine is a central-nervous system stimulant that it has been suggested can increase muscular strength in the short-term, increasing the calories burnt during workouts. It has a few associated health benefits like improved alertness and mood and even cancer risk reduction; but it also has negative effects on health in the long-term, like dependency and addiction, and in the short-term concentrated sources of caffeine can make it difficult to focus and cause ‘energy crashes’ when the effect wears off.
Green tea extract
Green tea is thought to be beneficial for weight loss. A herbal derivative of green tea leaves, it contains antioxidants that might help improve skin quality, improve brain health, and better liver functioning; there are many other potential health benefits associated with green tea including reduced cancer risk. The caffeine content and catechins might also help with weight loss, but this effect has not been confirmed.
Cha de Bugre (cordia salicifolia)
This comes from the Cha de Bugre tree native to Brazil; it is a red fruit commonly used as a tea, helped by its caffeine content. There is currently little evidence to suggest it has weight-loss properties, although many traits are claimed of it; although it has a reputation for decreasing obesity, studies have only found mild hypolipidemic effects (decreasing abnormal fat levels in the blood).
From Lepidium Meyenni, a herb from the Andes in Peru, the constituent of maca root is mostly carbohydrate, some protein, and some fibre and fats, along with useful nutrients like magnesium and carboxylic acids reported to affect the nervous system. Some suggest it can boost libido and sperm quality, but few there is little evidence to suggest it can act as a weight-loss aid, or increasing energy as its reputation suggests.
L-theanine is an amino acid that is primarily found in tea. Some suggest it has brain-boosting functions, reducing stress and increasing awareness in a similar fashion to caffeine; others suggest it has immune system effects. Few weight loss effects are reported, although high stress levels are often associated with obesity.
Popularly considered a ‘superfruit’, the pomegranate has many associated health benefits, but weight loss is not one of them, and there are no pomegranate weight loss studies available online.
Derived from the ‘guggul’ plant, this is allegedly a common ingredient in many supplements; it was once believed to decrease total cholesterol levels and levels of low-density lipoprotein, and some suggest it has hypolipidemic effects, but there needs to be more research carried out first.
Key Xenamine Ingredients
There are a number of ingredients in this product, though ingredient quantities are not revealed (other than for caffeine and chromium). The two main ingredients that are touted for having weight loss effects are caffeine and green tea extract. Caffeine is a central nervous system stimulant that is thought to improve focus and reduce physical fatigue; this could help combat the ‘drained’ feeling when carbohydrate levels in the body are low due to the increased metabolic rate, and help improve workouts to help burn more calories. Green tea is thought to aid metabolism boosting and fat burning.
Caffeine is thought to increase the metabolic rate, causing the body to break down its energy supplies and immediately increase the users energy – potentially improving athletic performance. However, once the effect wears off, there is usually an ‘energy slump’ and caffeine can cause unpleasant side effects.
Green Tea Extract
Green tea extract has been shown to increase the oxidation (use) of body-fat over other energy sources, which, coupled with a sensible diet of long-lasting carbohydrates, could help build up easily accessible carbohydrate stores and burn the more stubborn fat stores. There is also some evidence to suggest that green tea extract can reduce absorption of fat from food, and that GTE supplementation shows weight loss benefits, though this varies with ‘catechin’ concentration, and some of the studies were inherently flawed.
Of the eight main ingredients of Xenamine, five show potential weight-loss associated effects. Again, the concentrations of these ingredients (apart from caffeine and chromium) is not stated in Xenamine, and the environment in which these ingredients act-in the supplement with other ingredients, and inside humans might be different from the environments these trials are carried out in; even trials on animals do not necessarily translate to human effectiveness due to differences in digestive and metabolic processes.
There is debate about how chromium acts in the body; chromium is recognised as an essential mineral, but supplementation effects are uncertain. It affects the activity of insulin, the hormone that regulates blood sugar level, and low levels of chromium have been linked to diabetes. However, whilst essential, for non-obese individuals, chromium supplementation seems to have little effect.
A 2001 study on 44 overweight women saw half the group take chromium supplements and the others a placebo; after 12 weeks, there was no significant difference between the two groups.
In diabetic patients, two studies showed significant improvements in insulin sensitivity using this form of chromium; moreover chromium pincolate was shown to have significant effects on carbohydrate craving and appetite in depressed individuals over 8 weeks. Despite all this, there are no studies that conclude that chromium supplements can help with weight-loss.
There is evidence to suggest that caffeine can help with weight loss. Caffeine is a stimulant that might increase metabolic rate, decrease fatigue and increase muscular strength and alertness, all helping towards weight loss. A study by Esther-Lopez Garcia et.al in 2006 monitored the caffeine intake of healthy men and women from 1986-1998 and compared it to their weight change over this time. Though the trial wasn’t entirely perfect, a lower average weight gain was observed in high-caffeine patients than low caffeine patients.
One study by Warren GL et al. also showed that caffeine was found to have a small benefit to muscular endurance and strength, showing an average of 75 increase in knee extensor strength and a very small increase in endurance over 27 cases. This implies caffeine supplements can help improve workouts to burn more calories. However, long term high-caffeine diets have been shown to have negative effects, like depression and addiction; the short-term energy boost caffeine gives, followed by the crash afterwards, can lead to dependency.
A 1981 paper on the psychological effects of caffeine summarised by stating that high caffeine intake could lead to ‘psychological symptoms which resemble anxiety and depressive neuroses’, could ‘affect sleeping habits generally resulting in insomnia and hyperactivity’, and may cause ‘symptoms of mental illness’.
Green Tea Extract
There is mixed opinion on the effectiveness of GTE. Since it contains caffeine, it might have some small effects on metabolic rate, but whether it has any other effects is uncertain. A study from 2009 saw a group of twelve normal weight men take either GTE, caffeine, a placebo or other supplements and have their metabolic rates measured over the next 4 hours. The GTE group saw limited effects but the caffeine group showed significant increases in metabolic rate. However, a previous study from 2007 saw a group of mixed individuals take GT of two varieties for twelve weeks; the group with GT higher in ‘catechins’ saw greater weight loss than the other group, but weight loss was observed in both groups. The people took Green tea itself however, which contains caffeine.
Another study from 2007 tested the effects of GTE on the absorption of fats in the intestines in vitro; the results suggested GTE could reduce the rate of capture of lipids, leading to reduced fat absorption. Overall, there is mixed evidence for the success of GTE, and flawed and inconsistent trials mar its potential, but it could prove effective in the right environment.
Cha be Bugre
This ingredient has little evidence for helping with weight loss, but some studies have shown it capable of reducing hyperlipidemia (overconcentration of fat in the bloodstream). A study from Brazil in 2006 investigated the anti-obesity, appetite suppressant and hypolipidemic (opposite of hyperlipidemia) effects of Cha de Bugre, in rats, both diabetic and normal. Whilst none of the other effects were observed, the hypolipidemic effect was observed in both types of rat, with small decreases in blood-lipid levels. This doesn’t promise much for weight loss but could potentially reduce risk of disease and maybe decrease the amount of lipid absorbed from food.
This is the most uncertain ingredient of Xenamine. Some studies have shown gugglesterone to have potential health benefits; a study conducted in mice concluded that it could lower cholesterol. It also shows benefits as an anti-cancer drug.In terms of weight loss, one study showed that it could increase production of iodine from, and the metabolic rate of, the thyroid gland, in rats, and oxygen consumption by organs and muscle cells (a sign of increased metabolic rate). No weight-loss conclusions are drawn, increased metabolic rate leads to more calories burned, so there could be weight-loss connotations.
Xenamine Side Effects
The company claims that this product has no side effects, though this is not the case. There are no user reviews available online, making it hard to tell whether any adverse effects will occur; however, as mentioned above, caffeine is known to have both negative short-term effects, such as nausea and headaches, and long-term psychological effects. Chromium has been associated with damage to the kidneys and liver, along with posing a danger to diabetics, and even psychological problems. It is also possible for users to have allergic reactions to Xenamine’s ingredients or to experience bowel problems. If any symptoms are experienced, users should stop use and see a doctor immediately.
One of Xenamine’s main ingredients is caffeine. Long-term use of caffeine can lead to problems. Just like people get addicted to coffee, caffeine supplements provide a short-term ‘boost’, making users feel more alert and less tired, but then an energy slump when the effects wear off, which might lead to dependency. Nausea, headaches, anxiety and jitteriness are also often reported for caffeine.
Insomnia is a common complaint, since caffeine forces the brain into a state of alertness. There have also been links made between caffeine and high blood pressure and heart disease; a review summarising many clinical trials, from 2007, concluded that although moderate amounts of caffeine lower the risk of heart disease, high levels in new users created risk of heart disease.
Chromium has been linked to a few health problems. A few users reported kidney problems with high intake, so users with kidney problems should avoid Xenamine, and liver damage was also reported. Since chromium is involved in insulin action, it is possible for chromium supplements to dangerously lower blood sugar levels, especially in diabetics. Acute hepatitis has also been reported in isolated cases.
Chromium pincolate, potentially the form active in Xenamine, has been shown to cause acute tubular necrosis (death of the vessels lining the kidneys) when taken in certain supplements, leading to severe problems; the study in question made a direct link to non-FDA regulated supplements and their negative effects, which most certainly includes Xenamine. Otherwise, chromium is mostly safe, and the described effects are rare; but following any sign of problems, users should immediately stop taking Xenamine and consult a doctor.
How to Use
The manufacturers don’t give strict instructions on how to take Xenamine, nor about who should or shouldn’t take it or for how long. InnerVital, the company behind Xenamine, briefly state that ‘2 pills per day’ should be taken, again with no advised time limit. Considering the concentration of caffeine, with each 2 pill serving containing the same amount of caffeine as four or five cups of coffee, it is inadvisable to exceed this amount; national health guidelines advise no more than this amount of caffeine per day. No instruction is given on when to take Xenamine, but it is strongly in advised to take it before going to bed, since the caffeine will likely cause insomnia.
Xenamine.com don’t provide any guidelines on who should or shouldn’t take it. We would discourage pregnant women or under 18s from taking it, along with people with heart or blood conditions. Caffeine can raise blood pressure and acts as a powerful stimulant, so might not be suitable for all users. Considering the chromium content, which has been linked to organ damage and problems with diabetics, sufferers of kidney or liver diseases and diabetic individuals should also avoid Xenamine.
Who Makes It?
Although Xenamine.com don’t provide any information about the manufacturer, clicking on the email contact link reveals Xenamine to be made by InnerVital, a US based company that provide little information about themselves. They produce a wide range of products including diet-pills, male virility pills, vitamins and some bizarre supplements like anti-hangover and breast-enhancement pills.
They confusingly claim that each diet pill they sell is ‘the most effective’ supplement to aid weight loss- most use the same claimed effects. The company provides an address and a support email address, along with a live chat option, though none of these has been tested. It’s worth noting that their website is poorly organised, with spelling mistakes (even in their own product names), improper grammar, no company information, confusing and misleading jargon and non-professional language. However, the website scamadviser.com reports no suspicious activity within the website.
Better Business Bureau confirm the address and phone number of the company, but reveal that InnerVital operates from the same address as ‘Shop Top Diet Pills’, who reportedly don’t make any of their own products. 12 complaints are recorded against this company, 4 of them unsolved. ShopTop’s website is very similar to IV’s, uses many of the same images and has similar products. The lack of information provided by Xenamine’s website about this arrangement and the complaints registered decrease the trustworthiness of Xenamine.
Where to Buy Xenamine
There are few retailers that sell Xenamine, but the official website, InnerVital, and ShopTopDietPills all offer similar rates and return policies on Xenamine. The Xenamine website and ShopTop price a single carton at about £23, and InnerVital at about £24; both Xenamine.com and ShopTop offer a 45-day money-back guarantee, but InnerVital don’t specify a length of time – presumably it’s the same (since they’re the same company). Innervital offer slightly cheaper prices on multi-pack bundles, along with slightly cheaper shipping charges – £4.30 internationally rather than £5.50 offered by Xenamine.
There’s also a more expensive express delivery service available. Since they’re all the same company, they all share the same reputation and all have the same privacy and returns policy. It’s worth bearing in mind that buying from little known retailers with a suspicious product line is risky and consumers are advised to attempt to speak to an advisor before agreeing to purchase anything.
Does Xenamine Meet our Approved Criteria
Money-back-guarantee: There is mention of a 45-day money-back guarantee on the official website, but details of this offer are not available.
One-off payment: The product appears to be sold using a one-off payment.
Manufacturing Standard: There is no mention of manufacturing standards.
Accompanying Diet Plan: There does not appear to be an accompanying diet plan.
Ingredients and quantities disclosed: An ingredients list is available, but specific ingredient quantities are not provided.
Company contact details readily available: Full contact details are provided on the official website.
Xenamine does not meet our ‘Approved’ criteria as there is no information about the money-back guarantee and no mention of a diet plan. Some information is lacking from the official website, including manufacturing details and full ingredient details.
Xenamine is produced by a little-known company that provide little information about themselves; it has no user reviews online and the manufacturers use jargon and misleading terminology to oversell their product. Whilst some of the ingredients have been associated with weight loss in early studies, the long-term effects and safety of the product are uncertain. Xenamine would not be suitable for all groups of people and we would recommend consulting a doctor before taking it. There is mention of a money-back guarantee, though the details of this offer are not disclosed.Google+
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