XLS Medical Fat Binder Review & Side Effects 2015
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XLS Medical Fat Binder

XLS Medical is a marketed as a fat binder. The manufacturers claim that XLS Medical will start reducing the user’s weight after just three days and after four weeks there could be significant weight loss.


Below we have reviewed XLS Medical Fat Bunder against our review criteria to help consumers make an informed decision.

XLS Medical Fat Binder Pros
  • Key ingredient, Litramine, is supported by various clinical trials
  • Made by a reputable company and stocked by trustworthy retailers
XLS Medical Fat Binder Cons
  • Presents the risk of uncomfortable side-effects
  • Company don't offer money-back-gurantee

XLS Medical is marked as ‘Rejected’ as it fails to meet 3 points on our ‘Approved Criteria’. To find out more about how XLS Medical performed against our criteria click here.

XLS Medical Review

The manufacturers of XLS Medical Fat Binder claim that it can burn up to three times more fat than normal exercise alone.

XLS Medical Claimed Weight-Loss Benefits:

XLS Medical claims to have one of the four main weight loss factors: Fat Binding.

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How XLS Medical Fat Binder Works

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Made with Litramine and fat-soluble vitamins A, D and E, XLS Medical claims to work to bind your dietary fat in your stomach and release it through your waste products. When the dieter has eaten, the pill, in theory, interacts with the fat from the food and creates a fat-fibre complex that are too large to pass through the walls of the small intestine. Due to not being absorbed, the fat-fibre complex should pass naturally via the stool. This should prevent you absorbing the fat into your body, which may result in weight gain. After the fat binding phase the essential fat-soluble vitamins A, D and E are released and absorbed into the body. These vitamins claim to be important for your health, and with reducing fat, you reduce these vitamins.

The importance of Litramine
Litramine is the main ingredient in the XLS Medical tablets that does the hard work. It is derived from the opuntia ficus indica plant, this plant is a type of cactus that grows in Mexico. Litramine, which is manufactured by Inqpharm, is a natural fibre complex that attracts and binds fat preventing it from being absorbed into the body.

Litramine essentially works by using a combination of insoluble and soluble fibres to bind and eliminate the fat. The insoluble fibres are responsible for binding the dietary fats in the meal, in the upper part of the stomach through lipophilic interactions. Lipophilic is the ability of being dissolved or attached to lipids. This creates the large fat-fibre complexes. The soluble fibres are non-starch, mucilage type of polysaccharide, which is able to absorb water as they swell to form a stable fluid gel. The gel structure helps the fat-fibre complexes, which are formed during the lipophilic interactions. The large fat-fibre complexes are then protected from digestion and absorption and are then excreted out. It is due to the reduced digestion and absorption of fats from food that allows you to consume fewer calories that are available from dietary fats which should result in weight loss.

There are also claims that Litramine helps to give you a feeling of fullness and satisfaction after eating. The insoluble fibres provide a bulking effect while the soluble fibres build up the viscosity (stickiness) in the gastrointestinal tract. Both these fibres work together to affect the gastric distension (this is the uncomfortable inflation of the stomach caused by gas) and the gastric emptying (this is the emptying of food from the stomach into the duodenum) which is what gives you the feeling of fullness and satiety. Also consuming fibre helps to balance your blood sugar levels which helps to manage hunger and food cravings.

The company behind XLS Medical has launched a website called XLSrealstories.com which show cases the experience of 15 “ambassadors” who we understand are members of the public who have been incentivised to use XLS Medical and document their experiences.

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XLS Medicial Fat Binder Key Ingredients


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XLS Medical Fat Binder appears to be contrived of natural ingredients. The key ingredient in XLS medical fat binder pills is Litramine™. There have been clinical studies conducted on Litramine which have yielded results which suggest that Litramine may be able to aid fat reduction. The other ingredients are all vitamins, including vitamin A,D3 and E-acetate.

For more information, we recommend you read our XLS Medical Fat Binder Ingredients article.

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XLS Medical Clinical Studies

Clinical Researcher 538

What are clinical trials? Clinical trials are research studies that explore whether a medical strategy, treatment or device is safe and effective for humans. They are also used to show what medical approaches work best for certain illnesses. A lot of scientific research is done first before any clinical trial takes place, and then the next step is normally animal testing to see how the approach affects a living body, and if it could be potentially lethal. However, what does work well on animals in a laboratory environment wouldn’t necessarily work in the real world so that’s when tests on humans are needed.

At the time of writing, no clinical trials have been conducted on XLS Medical itself. There have, however, been trials conducted on the product’s ingredients, namely Litramine. So far, there have been two clinical trials on Litramine, the first trial tested 10 volunteers while the second trial tested 150 volunteers. XLS Medical uses the results from both of these trials to prove that their tablets work. So let’s look at the trials.

One trial was conducted in Germany with Caucasian volunteers in their own living environments. This lasted 12 weeks and the study titled ‘A natural fibre complex reduces body weight in the overweight and obese: a double-blind randomised, placebo controlled study’ can be found in the journal ‘Obesity, the official journal of the obesity society’. This clinical trial involved 150 overweight and obese adults, the study looked into the efficacy and safety of XLS Medical’s key ingredient Litramine IQP G-002AS in body and weight reduction. Each volunteer was advised on what kind of exercise to do and they were given a fixed diet plan of 2,500 calories with 30% fat content. After a two-week placebo run-in phase they were then divided and each half either received 3g daily of Litramine or a placebo. The results showed that the volunteers who took Litramine lost 5% more of their initial body weight compared to those who took the placebo, they also had more of a reduction in BMI, body fat and waist circumference. The study also showed that Litramine (IQP G-002AS) was well tolerated, and no adverse reactions were reported.

Another clinical trial was conducted in 2012. This study was a randomised, double-blind, placebo-controlled study. The results of this study showed that Litramine could be effective in promoting weight loss. More information on this study clinical trialscan be found here.

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Side Effects of XLS Medicial Fat Binder

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XLS Medical Fat Binder’s official website state that XLS Medical is ‘gentle on the digestive system’. This would therefore suggest that there are no side effects associated with taking the product.
A review on the efficacy and safety of Litramine yielded results which suggested that there were no relevant gastrointestinal side effects associated with Litramine. The review did, however note that faecal fat excretion is higher when taking Litramine than when not using it.

Looking at review on the efficacy and safety of Litramine XLS Medical’s Amazon page, there are many user reports claiming side effects. These include bloating, constipation, stomach pain, flatulence, diarrhoea, headaches and even sickness.

Reported Side Effect 1: Bloating
Many users of XLS Medical have found bloating to be a problem for them as soon as they start taking the pill. It is believed that the sudden increase in fibre is the cause of this. Fibre is an indigestible carbohydrate and abruptly increasing the amount by taking the tablets can cause gas and bloating. Not only does the extra fibre can cause bloating, if you eat rich and fatty foods which make you feel stuffed, rather than full, you can also feel the effects of bloating. Fat takes longer to digest, so it keeps the stomach full for longer, hence the bloating. So to reduce this you need to limit the amount of fat in your diet.

Bloating however, is also caused my many other things, so for many of those who experienced bloating while taking the tablets they might be experiencing this due to other factors. See the list below for the other causes of bloating:

  • Overeating (most common cause)
  • Eating too fast
  • Gas in the abdomen, about half of the gas in the digestive system is swallowed air. Bacteria in the gut that helps to digest your food produce the rest. If the gastrointestinal tract does not move it through efficiently, gas builds up in the intestines, which cause bloating and discomfort.
  • Drinking through a straw, chewing gum, drinking fizzy drinks and sucking boiled sweets are also other causes.

Reported Side Effect 2: Diarrhoea
This side effect isn’t very common, compared to the others. But for those that experience diarrhoea this could be down to the increased amount of fat in the diet. Due to how the XLS tablets work, some may feel that they have to increase the amount of fat that they eat, which is not necessarily the case. All eating extra fat achieves is oily stools and diarrhoea.

Eating too much fat however, isn’t the only cause of diarrhoea. It could be down to food poisoning, IBS (Irritable Bowel Syndrome), lactose intolerance and allergies. Diarrhoea can also follow constipation, which leads to the next known side effect.

Reported Side Effect 3: Constipation
>Many users of XLS Medical have stated that constipation was a huge problem for them while taking the tablets. This idea is confusing considering the amount of fibre that the tablets contain; fibre helps in that department you think. Well when you increase the amount of fibre, especially suddenly, and don’t make sure that you drink enough water you will find yourself suffering from constipation. The symptoms of constipation are stomach pains, flatulence, sickness and even headaches, which can explain the other side effects that people have noted.

Other causes of constipation include:

  • Not eating enough fibre
  • Change in lifestyle or diet
  • Limited privacy on the toilet
  • Ignoring the urge to pass stools
  • Immobility or lack of exercise
  • Being under or over weight
  • Anxiety or depression

What we can conclude is that the tablet itself might not necessarily cause the side-effects you might be experiencing after taking XLS Medical.

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How To Take

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It is recommended that you take two tablets after every meal daily; only on exception should you take three, if you’ve had a particularly high fat meal. You also shouldn’t take more than 6 in a day.

The official website states that missing a day can cause you to lose a day of weight loss. To help keep track of how many pills you have taken you can keep a pill tracker chart so you don’t forget.

To be successful in reducing and controlling your weight, you must be prepared for a long-term commitment and this includes eating the right foods and keeping active. Getting active doesn’t mean having to go to the gym, you can find a range of activities to do which cater for busy moms to older adults and even kids. Finally, you should make sure that you drink plenty of water throughout the day. Not only does it help to avoid constipation, sometimes your body confuses thirst for hunger so by keeping hydrated you reduce the risk of overeating. It has been advised that you should drink one large glass with each meal and one small glass between meals.
There are still certain types of people who shouldn’t take the tablets, these are:

  • Pregnant or likely to get pregnant
  • Women who are breastfeeding
  • Have a BMI less than 18.5
  • Eat liver or liver products once a week, with other products containing retinol (XLS contains Vitamin A as retinol)
  • Are at risk of osteoporosis

You should also consult your doctor before taking the tablets if:

  • You have diabetes
  • Use cholesterol reducing medication
  • Have an existing medical condition
  • You suffer from Kidney stones or kidney disease
  • Are taking any medicines

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Who Makes XLS Medical

The company behind XLS Medical is Omega Pharma who focus on health products. They sell a vast range of health products which expands beyond weight loss.

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Where to Buy XLS Medical


There are many places that you can purchase XLS Medical tablets from; these include internet and high street shops and even supermarkets. Prices vary from place to place; you can spend £35 to £65 just for a month’s worth of tablets.
The purchase options from Boots are as follows: you can either buy 60 tablets (10 days) for £25.99 or 180 tablets (a month) for £59.99.

Just like boots, Amazon only have two tablet quantities, you can buy either 120 tablets (20 days) for £20.99 or 180 tablets for £35.04.

There are six different tablet quantities from Lloyds Pharmacy. The lowest is 30 tablets (5-day trial) at £14.99 and the highest is 180 triple pack (3 months) at £169.97. There’s information available on the website page but no customer reviews.

From Superdrug you can get three different quantities, they are 30 tablets for £11.99 (original price £14.99), 60 tablets (10 days) for £19.99 (original price £24.99) and 180 tablets at £47.99 (original price £59.99). There is a section for reviews on the website but not many have contributed.

Tesco offers 60 tablets for £16.66 (original price £25) and 120 tablets for £32 (original price £48). There is information on the website page but it’s mostly the kind that you would find at the back of a tablet packet. There’s also no customer feedback.

McCabes is a Republic of Ireland pharmacy; there is only the 60-tablet option, which you can buy for €26.99/£23.10 (original price €29.99/£25.67). The website page has a detailed description of the product added with many informative diagrams, there is a space for comments but none has been made.

Sam McCauley is a Republic of Ireland beauty and health shop. There are two tablet quantity options available from here; you can have the 60 tablets for €29.99/£25.67 or 180 tablets for €64.99/£55.62.

Inhealth is another Republic of Ireland beauty and health shop. There is only the 60-tablet quantity for €26.99/£23.10 available. There’s general information about XLS Medical on the website page, and a section for feedback but not many comments have been received.

Pharmacy2u is the UK’s first internet pharmacy. There are three different tablet quantity amounts available from this website; they are 60 tablets at £17.45, 120 tablets at £32.99 and 180 tablets at £39.99. There is no delivery charge unless you want the items quicker.

Asda only offers the 30 tablet (5-day trial) which are £12, so unless you only plan to buy a trial your better off looking at the other places listed above.

So there you have it ten places where you can buy XLS Medical, as you can see the price does vary a lot so it’s just a choice of finding the price that’s right for you.

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Does XLS Medical Meet our Approved Criteria

Money-back-guarantee: No.

One-off payment: Yes, with prices ranging from £35 to £65 for a month’s supply.

Manufacturing Standard: Unknown.

Accompanying Diet Plan: No, however the official website offer dieting tips, promoting a healthy lifestyle.

Ingredients and quantities disclosed: Yes.

Company contact details readily available: Yes.

XLS Medical Fat Binder doesn’t meet our ‘Approved’ criteria as it does not offer a 30 day or more money-back-guarantee and we can’t find details of the manufacturing standard.


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Overall Verdict

XLS Medical Fat Binder’s key ingredient is Litramine which is supported by various clinical studies. Furthermore, XLS Medical is made by a well-known company with an established reputation.
However, no money-back-gurantee is offered and some side effects are likely to occur as a result of taking the product.

XLS Medical Direct Review

XLS Medical has now launched XLS Medical Direct, backed by a big TV advertising campaign. XLS Medical Fat Binder Direct sachets are very similar to XLS Medical Fat Binder. However, unlike XLS Medical Fat Binder which is taken in the form of pills, XLS Direct is taken as a powder straight in to your mouth without the need for water.

The apparent thinking behind coming in powder form is, that you will find the product easier to take. This review is still relevant for XLS Medical Direct, However, for more information, you can read our full XLS Medical Direct Review.

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Comparison With Other Fat Binders

We’ve compared XLS Medical with other fat binding products on the market to help you decide which is the best fat binder for you.

XLS Medical Vs Proactol

xls medical vs proactol diet pills

View our article comparing XLS Medical Vs Proactol Plus

XLS Medical Vs Rasva Diet Pills

xls medical vs rasva diet pills

View our article comparing XLS Medical Vs Rasva Fat Binder

XLS Medical Vs Boots Fat Control Tablets

xls medical vs boots fat control tablets

View our article comparing XLS Medical Vs Boots Fat Control Tablets

XLS Medical Vs Liposinol

xls medical vs liposinol diet pills

View our article comparing XLS Medical Vs Liposinol

XLS medical vs. Xipisan

xls medical vs xipisan

View our article comparing XLS Medical Vs Xipisan

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Comparison With Other Diet Pills

XLS Medical Vs Alli

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View our article comparing XLS Medical Vs Alli

XLS Medical Vs Adios Slimming Pills

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View our article comparing XLS Medical Vs Adios

XLS Medical Vs Orlistat

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View our article comparing XLS Medical Vs Orlistat

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32 Responses to “XLS Medical Fat Binder”

  1. Trace Barry says:

    I tried a 10 day treatment of XLS medical andf had no results whatsoever!

    • Tiffany Blake says:

      I’m glad to hear it’s not just me who didn’t find XLS effective. Has anyone had any luck asking for a refund?

  2. Genny H says:

    I tried XLS Medical for a while with diet and exercise and it had no effect :/ would not recommend at all.

    • Robyn says:

      Hi Genny, what kind of diet were you following? I’m surprised you didn’t at least lose some weight because of the diet if not xls?

      • Lee says:

        This is often the problem. You can’t simply take the pill and do nothing else. It helps (considerably) with your diet and if you didn’t lose any weight at all then you are not dieting!

  3. Tiffany Blake says:

    I had been on a diet for a few weeks, losing a pretty steady pound or two a week, I purchased XLS Medical tablets to give me a bit of a boost. I carried on following my diet, taking the tablets alongside and they didn’t seem to make any difference at all. I think some weeks it may have even slowed me down. I’d taken them as directed but I found I lost less while I was taking them and on top of that felt like my stomach was bloated too. I would definitely not recommend them, in my opinion they’re a waste of money.

  4. Karl Lawrence says:

    These pills started well for me, I lost about 5lbs in the first week. I took the pills, did a little more exercise and ate a little less. But then for the next few weeks I lost no more weight, despite still doing the exercise and slight diet. Bit disappointed and probably won’t be buying any more of them.

  5. Amy Herron says:

    I must say I was really disappointed in these pills. I only wanted to lose about 6 or 7 pounds as I’m pretty healthy already but they didn’t do anything, not even for an already fairly fit person.
    I believed the good reviews I’d read but they did nothing for me. I’m going to take long walks and fit in some more exercise instead, much cheaper and more effective option if you ask me!!

    • Paula says:

      Amy, just wondering whether you had much weight to lose. You say you’re already a fit person but I must admit I had more to lose and these pills did work for me!
      I wonder whether it might work on people with more to lose because I really found them quite effective and I’m going to continue to use them.
      Sad to hear they didn’t work for you though.

  6. Philippa says:

    I’ve been really happy with these pills, I have lost weight on them. I think they work best after fatty meals so my advice is eat lots of fatty foods.
    I’m going to buy more I think.

  7. Hayley Lowers says:

    These pills were fantastic! I’ve been trying to diet and searching for the right pill for five years now but these tablets have worked wonders….25lbs in 4 months!!
    I personally take 1 at breakfast, 2 at lunch and 3 after dinner because I believe they prevent fat going into your body and instead pass it out of your body. So I take 3 after dinner as its the most fatty meal.
    I’d suggest you set a reminder to take the pills because if you miss any then the whole day is wasted. I’d also recommend you drink plenty of water because of the high fibre content.
    Give them 2 weeks to get going but once they do you’ll really notice the difference. I happily recommend them!!

    • sonya says:

      Hi Hayley.
      Thanks for sharing your thoughts.
      I just bought a 10 day supply of this tablets because i wanted to try them.
      I weight 73.5 kg and i am 169 cm tall.I have my thyroid glands removed and is so hard for me to loose weight.
      I bought only 10 day supply because i am on thyroxine medication and i don,t know yet if i am going to have any side effects.
      If not, i will buy more and let everyone know my results.
      Thanks again and good luck.

  8. Jack says:

    I struggled to find successful reviews on XLS Medical so I wanted to share how my experience is going so far. I’m only a week into taking them but so far I’ve lost 3lbs!
    Admittedly I have quite a lot of weight to lose and I’ve made diet changes as well as trying to walk for half an hour a day. This means I can’t be 100% sure it’s the XLS that is helping the weight loss but I’m going to continue to take them and hopefully it continues.
    I’ve been a little bit more windy than usual on these pills but no constipation or anything like that.

  9. kerry says:

    Initially I was really impressed with these pills, I lost a little bit more weight in my first week taking them. Since then the weight loss has really slowed down and I think might have even stopped.
    I’m not going to bother buying any more once I’ve ran out, I wouldn’t bother taking them if I were you.

  10. G Innman says:

    I normally lose about 1 or 2 pounds a week when I’m dieting on my own. I’ve been taking xls medical for a week now and I’ve lost 4 pounds!! They’ve been a great help and I’m so glad I took the plunge and bought them.

  11. Nancy Parker says:

    I had high hopes for these pills but I lost very little weight at all. I followed the instructions properly and did everything I could to get the weight off but it didn’t work. They’re over priced and over rated, I won’t be buying again.

  12. Olivia Wilde says:

    So far so good with these pills! I’ve been taking them for a couple of weeks now alongside a high protein and high fibre diet. It’s all been working really well and I’ve lost weight each week so far. I wouldn’t recommend you take these without following a high fat diet because I think you’d experience some bad side effects.

  13. Abbie says:

    I’ve given these pills two weeks to work, like a lot of people and reviews have said but nothing.
    Should I keep going any longer? Is it worth it? At the moment I won’t be buying any more. I’ve lost virtually nothing even over a full two weeks taking them as instructed. Frustrating!!

    • Missy says:

      Hi Abbie, I think it’s worth it if you give it a third and final week. when I took xls I found it quite slow to begin with but it did kind of pick up in the third week. I have to admit I gave up after the fourth week. Hope you see some improvement if you continue!

    • joanie says:

      I would give it maybe one more week, possibly two. Sometimes these diet pills can be slow to start working, when I took them they took about three weeks to really start working. It was drastic weight loss from then but atleast it was something

    • Wendy says:

      No dot go by instructed drink loads water and exercise don’t eat loads food especially fatty food don’t gaive up yet and really exercise hard. Like I do

  14. dani says:

    I had an ok time taking xls. Only ok. I didn’t lose very much weight, to be honest I think I could have lost the same amount without them. On the other hand I didn’t experience any side effects and I did manage to lose some weight. Which is better than nothing.
    I don’t think I’d take them again but they weren’t as bad as I’ve read some people saying.

  15. harriet says:

    I feel this product is way overpriced for what it does.. I paid a lot of money and only saw very small weight loss so I’m quite disappointed with it. I’m guessing I probably could have lost the same amount of weight with proper dieting an exercise and I would have saved myself lots of money.

  16. Janice P says:

    I’m pretty happy after taking XLS. I’ve been taking it for about 5 or 6 weeks and so far I’ve lost about 12lbs or slightly more. I’ve been eating slightly less but nothing major. I didn’t really get any side effects either, I probably got more headaches than I used to. I couple of moments of stomach pains but nothing major.
    Overall, very happy!

  17. martina says:

    I’m not sure how I feel about xls medical fat binder. I’ve been taking them for about a month now and I’ve lost a little bit of weight, nothing dramatic but a little bit. The reason I’m not sure what to make of them is because I think for how expensive they are I’d expect more weight loss.
    As for side effects they weren’t really major, I suffered from the odd headache but that’s about it really. Mixed feelings overall, not worth the money I don’t think.

  18. Elena says:

    Hello everyone! I was interested in that product as it is popular tv ad. I am not into diet pills, exercise about 4 -5 times in a gym, try eat healthy. Sometimes, want to loose some weight to fit in clothes better. I am size 12-14, 32 years old female, 80 kg. sound a lot, but it’s muscles i hope:)
    We all want to think that we can slim nicely down by taking a miracle pill. I had some desperate moments myself, but no pill can read your mind what place of your body you want to shrink or what part of your body you are happy with.
    I know some people who seemed to loose their quirkiness by becoming skinny. It is important that you love yourself, the way you are, and people will except you and embrace it.
    It is a serious risk of getting permanent health problems if you taking some of the slimming pills, regardless you lost your weight when you were taking them or not. I am not a doctor, but the internal organs must deal with something that interupt their normal function if you swallowed some diet pill, like fat binder. It is not sound right.
    Please guys do not expect miracles when you taking diet pills. The word “diet” is from latin “way of life”. You see, even when i exercising, loosing 1 000 just on cardios i do not expect instant results, as the body must adapt about a month to that, altogether with eating healthy. I do not believe you can expect big positive weight loss in 5 days without any body damage, it’s laughable. You probably loosing your water, witch will make you feel dizzy and tired. Do not ruin your body, love yourself! Your body is a very complicated mechanism, respect that!

  19. Shirley says:

    I have been taking xls for a week and have terrible constipation has any one else suffered this ??

  20. Sue says:

    Reading these comments I’m not going to attempt them

  21. fetchmypony says:

    they’re far too expensive so I can’t afford to take them all the time but I’ve been having them throughout the last 12 months and have lost 3.5 stones with dieting. I take 2 tablets after a meal if I ate something fatty like a treat. When I eat v healthy meals I don’t use the tablets as there’s no need. I really do think they’ve helped and I did a lot of research before I purchased – medical research has proved they’re one of the v few drugs that actually do work.
    They do NOT make you feel full like some reviews say, they don’t make you feel anything at all! The only slight side effect I’ve noticed in all the time I’ve been taking them is a slightly looser bowel movement if I take max dosage for a couple of days – nothing particularly significant but I can imagine it might affect some people more. They’re worth the money – I still copper up to buy them whenever I can.

  22. frank robbins says:

    i have had terrible constipation whilst taking this tablet over a 4 week period, also wind/flatulence was increased tenfold. i was drinking about 8 glasses of water plus 8 mugs of tea n coffee, stopped them because of this and the fact i never lost 1 pound

  23. Wendy says:

    Well after reading some of the comments I think I’ll leave it for now and loose weight the way my husband does and drink loads water and go on a five mile walk every day with the dog. And live healthy ppl

  24. sukhjinder says:

    I tried full 30 days box and its the worst product ever. Bloated every day and also blood in my stole. Haven’t lost a gram on this stuff and never recommend to any body ever

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