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Sanafil is a weight loss supplement marketed by its manufacturers – Phytoscience LTD – as being the ‘all-natural way to reduce your appetite, fast’. Clinical evidence of its potential appetite-suppressing effects is lacking.

Below we have reviewed Sanafil against our review criteria to help consumers make an informed decision.

Sanafil Review

Sanafil Pros
  • Not associated with severe side effects
  • Some ingredients have been subject to early clinical study
Sanafil Cons
  • Product itself and some ingredients not clinically tested for potential weight loss benefits
  • No full ingredients list available

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Sanafil Review

Sanafil is promoted by its manufacturers as being a 100% natural supplement that can help you lose weight fast with few lifestyle changes. The main claim for Sanafil is that it is an effective appetite suppressant, which in turn means daily calorie intake will be lower so you naturally lose weight by not eating as much as you generally would. Evidence to support this claim is however not definitive.

Claimed weight loss benefits

The manufacturers claim Sanafil is an appetite suppressant, due to the inclusion of Korean Pine Nut Oil. It therefore is said to target one of the five key areas of weight loss.

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How Sanafil Works


The main ingredients in Sanafil include Korean pine nut oil, chromium picolinate, and vitamin B3, which the manufacture claims combine and result in the degradation of glucose and fat in the body, as well as the production of appetite suppressing hormones in the body. Sanafil supposedly works by employing Korean nut oil (extract) to act as a catalyst for smaller meal portions – thereby lowering calorie intake – and adding the potential weight loss inducing characteristics of vitamin B3 and chromium (in picolinate form).

Korean Pine Nut Oil

Sanafil contains the Korean pine nut oil; an ingredient that is thought to help to facilitate a weight loss regimen. Korean nut oil is rich in fatty acids, some of which are said to cause a chemical reaction in the body, which in turn supposedly initiates the release of appetite suppressing hormones – specifically Cholecystokinin (CCK). This might lead to a reduced desire to eat, curbs cravings and makes you want to consume less when you are eating.

Chromium Picolinate

Chromium is a mineral that the body requires – albeit in trace amounts. It is said to support the breakdown of fat, carbohydrates and protein in the body. The manufacturers also claim that it enhances the action of insulin, a critical hormone, which is heavily involved in the metabolism and storage of nutrients, particularly sugars.

Vitamin B3

Vitamin B3 (or niacin) is also known as being one of the most powerful of all the B-Complex vitamins. It is thought to help in the production and breakdown of glucose, fats and amino acids.

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Key Sanafil Ingredients

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The key ingredients that Sanafil is comprised of include Korean pine nut oil (extract), chromium picolinate and vitamin B3. Chromium is an essential mineral the body requires, and when combined with picolinic acid it is easier for the body to absorb. Both chromium picolinate and vitamin B3 (or niacin) are asserted to support in breaking down glucose, amino acids etc. and making the metabolism more efficient. However, while boosting the Metabolism does have indirect effects for facilitating weight loss this must be paired with a healthy lifestyle to have a tangible effect. There have been studies on the weight loss properties of chromium picolinate, that have in fact found that it may be antithetical for direct weight loss, in other words it contributes to weight gain.

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Clinical Studies

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It is important to note that there have been no systematic trials of Sanafil by itself; however, there have been a number or studies regarding how the ingredients it is composed of help facilitate more effective weight loss.

Korean Pine Nut Oil (Extract)

Korean pine nut oil is a vegetable oil extracted from the edible seeds of the ‘Korean Pine Tree’. Studies have suggested that “pine nut oil may have potential as a dietary supplement for preventing obesity and metabolic dysfunction…” Further studies also endorse Korean pine nut oil with a paper presented in an American Physiological Society session reporting that in a randomised double blind study showed that 18 women experienced a reduced desire to eat.

Chromium Picolinate

Chromium picolinate is a combination of chromium and picolinic acid. Chromium is an essential mineral for the body as it aids in the transport of blood glucose across cell membranes. However, in most diets not enough chromium is ingested due to it being stripped from foods that are processed – as a result the FDA recommends a daily chromium intake of approximately 130mcg. By combining chromium with picolinic acid, the rate of chromium absorption within the body is made more efficient.

It is claimed that Chromium picolinate has the ability to reduce fat while maintaining and in fact increasing lean muscle mass. Scientific research has however been largely unsupportive of these claims. One such study on the effects of chromium picolinate on body composition found that it did not facilitate any significant weight loss over the trial period. Half the participants were given 400mcg of chromium picolinate a day whereas the other half were given a placebo. The results indicated that there were no differences between the two groups and though both lost weight, this was attributed to the exercise regimen that accompanied the trial of the supplement.

More troubling is the finding that chromium supplementation without exercise may actually produce a significant increase in body weight on top of its lack of effect on enhancing weight loss.

Vitamin B3 (Niacin)

Incorporating Vitamin B3 in your diet is a prerequisite for having a healthy balance of minerals and vitamins. Vitamin B3 is especially known for improving cholesterol levels. The vitamin is also vital in that it releases energy from carbohydrates, fats and proteins so that the body can use them. Essentially, niacin should have an effect on the metabolism, and is therefore relevant to weight loss as it helps efficiently metabolize carbohydrates, fats and protein. It is also important to the health of the digestive system, skin and nerves.

However, when it comes to the direct weight loss properties of Vitamin B3, the benefits stop. While it might be good for general health, it was actually found to act as an appetite stimulant (opposite of appetite suppressant) in one 2010 study.

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Sanafil Side Effects

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The main precaution to take before taking Sanafil is to make sure that you have no nut allergies as it may be unsuitable and even dangerous for you, this goes the same for those with outstanding health conditions like liver and kidney problems, as well as diabetes. The side effects that are present – such as nausea and vomiting, are only relevant when the ingredients contained in Sanafil are taken in high doses. The daily dosage of Sanafil if you are following the guidelines is below this amount so for most people it should be safe.

As with any course of dietary supplements, it is highly recommended before undertaking it that you go and visit your doctor and inform them of your intentions.

Korean Pine Nut Oil

The most common side effect associated with any type of pine nut, including the Korean pine nut is an allergic reaction. If you have known allergic reactions to peanuts, or other nut allergies, it is highly recommended that you see your doctor first. The most common allergic reaction symptoms include: itchiness, hives, red rashes, watery eyes and runny nose, abdominal cramps, nausea, diarrhoea, and vomiting.

Chromium Picolinate

There is a distinct lack of research regarding the side effects that may be associated with chromium picolinate. However, it is noted to be “likely safe” for most people if used sensibly. There have been reported side effects including: skin irritation, dizziness, nausea, headaches, and mood changes. Additionally, it should be taken into account that if you are an expecting (or breastfeeding) mother chromium picolinate should only be taken if recommended by a practicing health professional. Also it is unsuitable for people who know they have liver disease (or dysfunction), diabetes, cancer or a weakened immune system.

Vitamin B3

Vitamin B3 is essential for a healthy life, however if taken in very high doses (without professional guidance) there can be a number of side effects. The most widely reported is ‘niacin flush‘ – which is a burning, tingling sensation in the face and chest and is accompanied by red (or flushed) and blotchy skin. Also when taken in high doses, niacin can lead to stomach ulcers and liver damage. It is also unsuitable for people with low blood pressure, as well as those with a history of liver disease, kidney disease and diabetes.

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How to Use

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The official website informs its customers that two capsules need to be taken twice a day. For those who are not keen on swallowing tablets, you can mix them with jam, honey or yogurt. The times to take Sanafil varies, if you are a snacker then you need to take the capsules 2 hours after breakfast and 2 hours before your evening meal. If you however, overeat at meal times you should take 2 capsules 20-30minutes before lunch and 20-30 minutes before your evening meal.

It is also claimed that you do not need to make any major adjustments in lifestyle or diet for Sanafil to have an effect, but it is recommended that you take on an exercise program and follow a healthy diet for the best effects. Do not take if you are pregnant or breastfeeding. Consult a doctor before taking if you have a pre-existing medical condition.

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Who Makes It?

The company behind Sanafil is known as Phytoscience LTD. They are based in Scotland and have been active since 1998, and were formally known as Linpharma Ltd. The company distributes other health products around the UK – acting as a wholesaler to health food stores and pharmacies. They claim to be focused on bringing the customer the best natural health and beauty products.

Overall, the company seems to be reputable and manages a number of sites such as Natural Figure and Natural Woman. There are links to social media and customers can pay by Paypal, but there is no full ingredients list, no diet plan, and no mention of a money-back guarantee.

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Where to Buy Sanafil


Sanafil is currently only available for online purchase with the most popular place being via the official Sanafil website – however, it should be noted that the actual purchase is done through the manufacturers recommended retailer ‘Just You’. Here, a box of 60 capsules costs £34.95 plus an additional postage charge. The only other easily available place to purchase Sanafil is Amazon. Here it is currently available for the cheaper price of £21.45 for 60 capsules. Again though, there are no customer reviews regarding Sanafil.

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Does Sanafil Meet our Approved Criteria

Money-back-guarantee: There is no mention of a money-back guarantee on the official website.

One-off payment: The product appears to be sold using a one-off payment.

Manufacturing Standard: There is no mention of manufacturing standards.

Accompanying Diet Plan: There does not appear to be an accompanying diet plan.

Ingredients and quantities disclosed: A full ingredients list is not provided.

Company contact details readily available: Full contact details are provided on the official website.

Sanafil does not meet our ‘Approved’ criteria as there is no money-back guarantee or diet plan and some information is lacking from the official website, including manufacturing details and a full ingredients list.

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Overall Verdict

Sanafil contains ingredients that might be beneficial for the general health and maintenance of the body. However, the product as a whole has not been clinically tested and none of the ingredients have been definitively proven to aid weight loss in clinical studies. The product is unlikely to have severe side effects for some people, though it is not suitable for certain groups (including those with nut allergies). The company behind the product appears to be small; there is no diet plan or money-back guarantee and a full ingredients list is not disclosed.

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